P65253
Gene name |
lldP (lctP, c4425) |
Protein name |
L-lactate permease |
Names |
|
Species |
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) |
KEGG Pathway |
ecc:c4425 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P65253
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P65253-F1 | Predicted | AlphaFoldDB |
No variants for P65253
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P65253 | |||||
No associated diseases with P65253
No regional properties for P65253
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P65253 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| lactate transmembrane transporter activity | Enables the transfer of lactate from one side of a membrane to the other. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNLWQQNYDP | AGNIWLSSLI | ASLPILFFFF | ALIKLKLKGY | VAASWTVAIA | LAVALLFYKM |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PVANALASVV | YGFFYGLWPI | AWIIIAAVFV | YKISVKTGQF | DIIRSSILSI | TPDQRLQMLI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VGFCFGAFLE | GAAGFGAPVA | ITAALLVGLG | FKPLYAAGLC | LIVNTAPVAF | GAMGIPILVA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GQVTGIDSFE | IGQMVGRQLP | FMTIIVLFWI | MAIMDGWRGI | KETWPAVVVA | GGSFAIAQYL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SSNFIGPELP | DIISSLVSLL | CLTLFLKRWQ | PVRVFRFGDL | GASQVDMTLA | HTGYTAGQVL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RAWTPFLFLT | ATVTLWSIPP | FKALFASGGA | LYEWVINIPV | PYLDKLVARM | PPVVSEATAY |
| 370 | 380 | 390 | 400 | 410 | 420 |
| AAVFKFDWFS | ATGTAILFAA | LLSIVWLKMK | PSDAISTFGS | TLKELALPIY | SIGMVLAFAF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ISNYSGLSST | LALALAHTGH | AFTFFSPFLG | WLGVFLTGSD | TSSNALFAAL | QATAAQQIGV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| SDLLLVAANT | TGGVTGKMIS | PQSIAIACAA | VGLVGKESDL | FRFTVKHSLI | FTCMVGVITT |
| 550 | |||||
| LQAYVLTWMI | P |