Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P64166

Entry ID Method Resolution Chain Position Source
AF-P64166-F1 Predicted AlphaFoldDB

No variants for P64166

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P64166

No associated diseases with P64166

4 regional properties for P64166

Type Name Position InterPro Accession
domain FtsK domain 412 - 629 IPR002543
domain AAA+ ATPase domain 442 - 624 IPR003593
domain FtsK gamma domain 704 - 767 IPR018541
domain FtsK alpha domain 300 - 400 IPR041027

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
  • Located at the septum
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

3 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
chromosome segregation The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MANKNTSTTR RRPSKAELER KEAIQRMLIS LGIAILLIFA AFKLGAAGIT LYNLIRLLVG
70 80 90 100 110 120
SLAYLAIFGL LIYLFFFKWI RKQEGLLSGF FTIFAGLLLI FEAYLVWKYG LDKSVLKGTM
130 140 150 160 170 180
AQVVTDLTGF RTTSFAGGGL IGVALYIPTA FLFSNIGTYF IGSILILVGS LLVSPWSVYD
190 200 210 220 230 240
IAEFFSRGFA KWWEGHERRK EERFVKQEEK ARQKAEKEAR LEQEETEKAL LDLPPVDMET
250 260 270 280 290 300
GEILTEEAVQ NLPPIPEEKW VEPEIILPQA ELKFPEQEDD SDDEDVQVDF SAKEALEYKL
310 320 330 340 350 360
PSLQLFAPDK PKDQSKEKKI VRENIKILEA TFASFGIKVT VERAEIGPSV TKYEVKPAVG
370 380 390 400 410 420
VRVNRISNLS DDLALALAAK DVRIEAPIPG KSLIGIEVPN SDIATVSFRE LWEQSQTKAE
430 440 450 460 470 480
NFLEIPLGKA VNGTARAFDL SKMPHLLVAG STGSGKSVAV NGIIASILMK ARPDQVKFMM
490 500 510 520 530 540
VDPKMVELSV YNDIPHLLIP VVTNPRKASK ALQKVVDEME NRYELFAKVG VRNIAGFNAK
550 560 570 580 590 600
VEEFNSQSEY KQIPLPFIVV IVDELADLMM VASKEVEDAI IRLGQKARAA GIHMILATQR
610 620 630 640 650 660
PSVDVISGLI KANVPSRVAF AVSSGTDSRT ILDENGAEKL LGRGDMLFKP IDENHPVRLQ
670 680 690 700 710 720
GSFISDDDVE RIVNFIKTQA DADYDESFDP GEVSENEGEF SDGDAGGDPL FEEAKSLVIE
730 740 750 760
TQKASASMIQ RRLSVGFNRA TRLMEELEIA GVIGPAEGTK PRKVLQQ