Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

22 structures for P62653

Entry ID Method Resolution Chain Position Source
4KVB X-ray 420 A J 1-105 PDB
4V4J X-ray 383 A k 1-105 PDB
4V63 X-ray 321 A AJ/CJ 1-105 PDB
4V67 X-ray 300 A AJ/CJ 1-105 PDB
4V7P X-ray 362 A AJ/DJ 3-100 PDB
4V83 X-ray 350 A AJ/CJ 3-100 PDB
4V84 X-ray 340 A AJ/CJ 3-100 PDB
4V9J X-ray 386 A AJ/CJ 3-101 PDB
4V9K X-ray 350 A AJ/CJ 3-101 PDB
4V9L X-ray 350 A AJ/CJ 3-101 PDB
4V9M X-ray 400 A AJ/CJ 3-101 PDB
4V9N X-ray 340 A AJ/CJ 3-100 PDB
4V9Q X-ray 340 A BJ/DJ 3-100 PDB
4W29 X-ray 380 A AJ/CJ 3-101 PDB
4XEJ X-ray 380 A AS10/BS10 3-100 PDB
5J4D X-ray 310 A SA/XC 1-105 PDB
5V8I X-ray 325 A 1j/2j 1-105 PDB
6B4V X-ray 340 A SA/WC 1-105 PDB
6BOH X-ray 340 A TA/YC 1-105 PDB
6BOK X-ray 355 A RA/UC 1-105 PDB
6N1D X-ray 320 A AS10/BS10 2-105 PDB
AF-P62653-F1 Predicted AlphaFoldDB

No variants for P62653

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P62653

No associated diseases with P62653

2 regional properties for P62653

Type Name Position InterPro Accession
conserved_site Ribosomal protein S10, conserved site 27 - 42 IPR018268
domain Ribosomal protein S10 domain 5 - 99 IPR027486

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.
ribosome An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.

2 GO annotations of molecular function

Name Definition
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.
tRNA binding Binding to a transfer RNA.

1 GO annotations of biological process

Name Definition
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPKIRIKLRG FDHKTLDASA QKIVEAARRS GAQVSGPIPL PTRVRRFTVI RGPFKHKDSR
70 80 90 100
EHFELRTHNR LVDIINPNRK TIEQLMTLDL PTGVEIEIKT VGGGR