Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for P62609
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1L4I | X-ray | 220 A | A/B | 22-227 | PDB |
| AF-P62609-F1 | Predicted | AlphaFoldDB |
No variants for P62609
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P62609 | |||||
No associated diseases with P62609
3 regional properties for P62609
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | GTP cyclohydrolase I, conserved site | 98 - 114 | IPR018234-1 |
| conserved_site | GTP cyclohydrolase I, conserved site | 146 - 156 | IPR018234-2 |
| domain | GTP cyclohydrolase I domain | 41 - 218 | IPR020602 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| outer membrane-bounded periplasmic space | The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cell wall organization | A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. |
| chaperone-mediated protein folding | The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRIWAVLASF | LVFFYIPQSY | AGVALGATRV | IYPEGQKQVQ | LAVTNNDDKS | SYLIQSWIEN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AEGKKDARFV | ITPPLFSMQG | KKENTLRIID | ATNGQMPEDR | ESLFWVNVKA | IPAMDKAKTG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ENYLQFAIVS | RIKLLYRPQG | LVIPPEQAPG | KLEFTRENGG | LTLFNPTPYY | LTVTDLKAGN |
| 190 | 200 | 210 | 220 | ||
| KSLENTMVPP | QGKVTVNIPG | GYTGGDITYK | TINDYGALTE | QVKGVVK |