P62511
Gene name |
NRK1 (AGR342C) |
Protein name |
Nicotinamide riboside kinase |
Names |
NRK, NmR-K, Nicotinic acid riboside kinase, Ribosylnicotinamide kinase, RNK, Ribosylnicotinic acid kinase |
Species |
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) |
KEGG Pathway |
ago:AGOS_AGR342C |
EC number |
2.7.1.22: Phosphotransferases with an alcohol group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P62511
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P62511-F1 | Predicted | AlphaFoldDB |
No variants for P62511
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P62511 | |||||
No associated diseases with P62511
No regional properties for P62511
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P62511 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.1.22 | Phosphotransferases with an alcohol group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| metal ion binding | Binding to a metal ion. |
| ribosylnicotinamide kinase activity | Catalysis of the reaction: N-ribosylnicotinamide + ATP = ADP + 2 H(+) + nicotinamide mononucleotide. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| NAD biosynthesis via nicotinamide riboside salvage pathway | The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD) from the vitamin precursor nicotinamide riboside. |
| nicotinamide riboside metabolic process | The chemical reactions and pathways involving nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide. |
| phosphorylation | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTSQLAGFKG | TRGTLLVGIG | GCSSSGKSTI | AKLAVQVLED | AVLVHQDDFY | RHDDEVPFDE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EYQIGNWDVP | EALDMAQFER | ELDHIRATGR | PAAKLVHNGN | IDDVGKFGIS | EEYLEELRRR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YRGRISQPVV | LVDGFMLYHD | DKVAARFDCR | LLVRAPYATM | KARRASRGGY | KTLDSFWQDP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PFYFDKFVYK | SYAATHARLF | RNCDVEDRLV | APDVQEIYNG | DEAQITCVLE | QVLDAIAAAQ |
| C |