P61743

PR
Gene name
gpsA1
Protein name
Glycerol-3-phosphate dehydrogenase 1 [NAD(P)+]
Names
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1
Species
Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10) (Mycobacterium paratuberculosis)
KEGG Pathway
mpa:MAP_3020c
EC number
1.1.1.94: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

9-82 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P61743

Entry ID Method Resolution Chain Position Source
AF-P61743-F1 Predicted AlphaFoldDB

No variants for P61743

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P61743

No associated diseases with P61743

2 regional properties for P61743

Type Name Position InterPro Accession
domain Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal 177 - 322 IPR006109
domain Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal 1 - 155 IPR011128

Functions

Description
EC Number 1.1.1.94 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
glycerol-3-phosphate dehydrogenase complex An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate.

2 GO annotations of molecular function

Name Definition
glycerol-3-phosphate dehydrogenase [NAD+] activity Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+.
NAD binding Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.

5 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
glycerol-3-phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of glycerol-3-phosphate, a phosphoric monoester of glycerol.
glycerol-3-phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of glycerol-3-phosphate, a phosphoric monoester of glycerol.
glycerophospholipid metabolic process The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
phospholipid biosynthetic process The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGAGAWGTAL AKVLVDAGGP GTEVTLWARR PELAERINAT RSNPDYLPGT SLPPGIHATA
70 80 90 100 110 120
DAGEALRDAT TVLLGVPAQA MRANLERWAP LLRDGATLVS LAKGIELGTL MRMSQVIVSV
130 140 150 160 170 180
TGVDPAQVAV ISGPNLASEI AACQPAATVV ACSDSGRAVA LQRMLNSGYF RPYTNSDVVG
190 200 210 220 230 240
TEIGGACKNV IALACGMAAG VGLGENTAAA IITRGLAEIM RLGIALGAKG ATLAGLAGVG
250 260 270 280 290 300
DLVATCSSPH SRNRSLGERL GRGATIGSVL AGSPDGGDGH VVEGVTSCQS VLALAASYDV
310 320 330
EMPLTDAVHR VCHKGLSVDE AMALLLGRRT KPE