P61666

PR
Gene name
mutS
Protein name
DNA mismatch repair protein MutS
Names
Species
Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough)
KEGG Pathway
dvu:DVU_1649
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

790-893 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P61666

Entry ID Method Resolution Chain Position Source
AF-P61666-F1 Predicted AlphaFoldDB

No variants for P61666

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P61666

No associated diseases with P61666

5 regional properties for P61666

Type Name Position InterPro Accession
domain DNA mismatch repair protein MutS, C-terminal 631 - 823 IPR000432
domain DNA mismatch repair protein MutS-like, N-terminal 9 - 120 IPR007695
domain DNA mismatch repair protein MutS, core 275 - 614 IPR007696
domain DNA mismatch repair protein MutS, connector domain 129 - 257 IPR007860
domain DNA mismatch repair protein MutS, clamp 451 - 541 IPR007861

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent DNA damage sensor activity A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.
damaged DNA binding Binding to damaged DNA.
mismatched DNA binding Binding to a double-stranded DNA region containing one or more mismatches.

1 GO annotations of biological process

Name Definition
mismatch repair A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTNPSPKLTP MFEQYLRIKE DYPDALLFYR MGDFYELFFD DAETTARELQ IALTCRNPNA
70 80 90 100 110 120
ELKAPMCGVP YHAVEGYISQ LLDKGYRVAI CEQIEDPKEA KGLVKRAVTR VLTPGTVIDD
130 140 150 160 170 180
ANLDAKEHNY LGALFWNQDA EAGAFAWVDV STGEWSGLYS RKLAELWQWA QKMAPRELLL
190 200 210 220 230 240
PEGVDTPAMA TLGTTQTVRV PARSHFDLKS GTERVMRAQG VADLGSLGLE GKPELVRACA
250 260 270 280 290 300
ALLAYLAQTQ KQELSHLAPF KPLNLGRHLI IDEVTERNLE LFHRLDGRKG PGTLWHILDR
310 320 330 340 350 360
TLTPMGGRLL EERMHHPWRE ASPIRETQQV VEWLFQDDVR REALRTALDL VYDLERLSTR
370 380 390 400 410 420
IFLNRATPKD FIALRQSLSA LPAVRATLER PANPEGTYPT DAETSGDTLP KPLSDMLSAW
430 440 450 460 470 480
DDLADYADLL RRALTDNPPH LVTEGGLFRP GFDPDLDELL DLAEHGEARL QELLAEEQTV
490 500 510 520 530 540
SGLPKLKLGY NRVFGYFFEL SRAGADSVPE HFVRRQTLAN AERFTTERLK ELEEKLVSAT
550 560 570 580 590 600
DRRKTLEYRL FQSLRDTVAE ARPRVLFMAD MLAHLDFWQS LADVARRNGW VRPDVHTGHD
610 620 630 640 650 660
IVIREGRHPV VEAMQGSASF VPNDLRMDEK RRLLLITGPN MAGKSTVLRQ TAIICLLAQM
670 680 690 700 710 720
GAFVPAREAS IGIADRIFSR VGASDNLAQG QSTFMVEMME TARILRQASK RSLVILDEIG
730 740 750 760 770 780
RGTSTFDGMA LAWAVVEELT RRAGGGIRTL FATHYHEITS LEGRIPGVHN MNIAIREWNG
790 800 810 820 830 840
DIVFLRRLVP GPADKSYGIE VARLAGVPHS VVQRARELLA DLERTRDAAR GTNSAPSRQT
850 860 870 880 890 900
LPGLDLPSKQ EQVDTIVAPP PCSGVEHPLL VALRDIDTDD MTPLEALKRI TEWKQLWGTT
REDRS