P61401

PR
Gene name
gatD (NEQ126)
Protein name
Glutamyl-tRNA(Gln) amidotransferase subunit D
Names
Glu-ADT subunit D
Species
Nanoarchaeum equitans (strain Kin4-M)
KEGG Pathway
neq:NEQ126
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

18-89 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P61401

Entry ID Method Resolution Chain Position Source
AF-P61401-F1 Predicted AlphaFoldDB

No variants for P61401

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P61401

No associated diseases with P61401

4 regional properties for P61401

Type Name Position InterPro Accession
domain L-asparaginase, N-terminal 72 - 253 IPR027474
active_site Asparaginase/glutaminase, active site 2 145 - 155 IPR027475
domain GatD, N-terminal 16 - 48 IPR040918
domain Asparaginase/glutaminase, C-terminal 283 - 386 IPR040919

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
asparaginase activity Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity Catalysis of the reaction: L-glutamine + glutamyl-tRNA(Gln) + ATP = L-glutamate + glutaminyl-tRNA(Gln) + phosphate + ADP.

3 GO annotations of biological process

Name Definition
cellular amino acid metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
regulation of translational fidelity Any process that modulates the ability of the translational apparatus to interpret the genetic code.
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVGELYRFIT DFGVIEGYII KEEPNYYLIK LKNGYNIGIK KSQIKEMENL NEKIKVGQFP
70 80 90 100 110 120
KRKPKGIGNL GFIYTGGTIG SKVDYLTGGV SAIMDIEELL AIADLPYDIK IIDSPFVKFS
130 140 150 160 170 180
EDLNPKDWVE IVKSIERTYK KGAEGIIVAH GTDTMHFSSA YAYYALENPI PIAFTGAQRS
190 200 210 220 230 240
SDRASTDAVI NLFASSIYAN SNIGEVAIVM HETINDDTAI AIRGISARKM HSTRRDAFKS
250 260 270 280 290 300
INEEPLARIY YPSGKLEIIN KKYRKRSDKE MVAKPYLDTK GALIWVYPGF DPSILEYYRN
310 320 330 340 350 360
YRGIIIAGTG MGHTSKELIP MLKELSKDLF IGITTQCIYG ITHPYVYSRG RELSKFATYL
370 380 390
QGTPEKNYVK LLYVLGKESD LDGIKKEMKR LP