P61268

PR
Gene name
STX1B (STX1B2)
Protein name
Syntaxin-1B
Names
Syntaxin-1B2
Species
Ovis aries (Sheep)
KEGG Pathway
oas:443479
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

114-218 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P61268

Entry ID Method Resolution Chain Position Source
AF-P61268-F1 Predicted AlphaFoldDB

No variants for P61268

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P61268

No associated diseases with P61268

3 regional properties for P61268

Type Name Position InterPro Accession
domain Target SNARE coiled-coil homology domain 186 - 278 IPR000727
domain Syntaxin, N-terminal domain 24 - 226 IPR006011
conserved_site Syntaxin/epimorphin, conserved site 197 - 236 IPR006012

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Single-pass type IV membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
SNAP receptor activity Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.
SNARE binding Binding to a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.

4 GO annotations of biological process

Name Definition
intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
neurotransmitter transport The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.
regulation of exocytosis Any process that modulates the frequency, rate or extent of exocytosis.
vesicle-mediated transport A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKDRTQELRS AKDSDDEEEV VHVDRDHFMD EFFEQVEEIR GCIEKLSEDV EQVKKQHSAI
70 80 90 100 110 120
LAAPNPDEKT KQELEDLTTD IKKTANKVRS KLKAIEQSIE QEEGLNRSSA DLRIRKTQHS
130 140 150 160 170 180
TLSRKFVEVM TEYNATQSKY RDRCKDRIQR QLEITGRTTT NEELEDMLES GKLAIFTDDI
190 200 210 220 230 240
KMDSQMTKQA LNEIETRHNE IIKLETSIRE LHDMFVDMAM LVESQGEMID RIEYNVEHSV
250 260 270 280
DYVERAVSDT KKAVKYQSKA RRKKIMIIIC CVVLGVVLAS SIGGTLGL