P61003
Gene name |
hisC |
Protein name |
Histidinol-phosphate aminotransferase |
Names |
Imidazole acetol-phosphate transaminase |
Species |
Methanococcus maripaludis (strain S2 / LL) |
KEGG Pathway |
mmp:MMP1216 |
EC number |
2.6.1.9: Transaminases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P61003
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P61003-F1 | Predicted | AlphaFoldDB |
No variants for P61003
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P61003 | |||||
No associated diseases with P61003
1 regional properties for P61003
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Aminotransferase, class I/classII | 36 - 363 | IPR004839 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.6.1.9 | Transaminases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| histidinol-phosphate transaminase activity | Catalysis of the reaction: L-histidinol-phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. |
| pyridoxal phosphate binding | Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| histidine biosynthetic process | The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSIDDKVRSI | VKEFKAYVPG | KSKEEIARNY | GIDPERIIKL | GSNENPWGCS | PKIEEKLLNE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VSNLHQYPQP | INPELMDEIS | KFTKMPVENI | IVGGDGADEV | IDNIMRILID | EGDEVIIPIP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TFTQYAISAK | IHGANIKWAK | FDEENGFKLD | VESVLNNITE | KTKAIFLCTP | NNPTGNVIPT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EDIKKIVEST | DALVMIDHAY | IEYSKEEYDL | TSWALKYDNV | LVLRTFSKVF | GLAGQRVGYG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VTSKKVVDYM | MRIKPIFSLT | RASQVSAITA | LQDKEFFEKC | LKEGIESREE | IYNGLKKFKQ |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LEVYPTEANY | MLVKVKNGMN | SSEFCEALLK | KGVIVRDCYS | FEGLEPYYFR | VSIGTSEENE |
| 370 | |||||
| RFLKIMSEIV | E |