P60837
Gene name |
hisZ |
Protein name |
ATP phosphoribosyltransferase regulatory subunit |
Names |
|
Species |
Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) |
KEGG Pathway |
gsu:GSU3307 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P60837
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P60837-F1 | Predicted | AlphaFoldDB |
No variants for P60837
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P60837 | |||||
No associated diseases with P60837
5 regional properties for P60837
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | S-adenosylmethionine synthetase, N-terminal | 2 - 99 | IPR022628 |
| domain | S-adenosylmethionine synthetase, central domain | 113 - 252 | IPR022629 |
| domain | S-adenosylmethionine synthetase, C-terminal | 254 - 387 | IPR022630 |
| conserved_site | S-adenosylmethionine synthetase, conserved site | 115 - 125 | IPR022631-1 |
| conserved_site | S-adenosylmethionine synthetase, conserved site | 280 - 288 | IPR022631-2 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| histidine-tRNA ligase activity | Catalysis of the reaction: ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| histidine biosynthetic process | The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. |
| histidyl-tRNA aminoacylation | The process of coupling histidine to histidyl-tRNA, catalyzed by histidyl-tRNA synthetase. The histidyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3''-OH group of a histidine-accetping tRNA. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTPITPIEAP | LPKGVTDFLP | EKADKIGYIE | GKIRKVFELW | GFRRIITPLL | EFEDVIAAGL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GDDLKAKTFR | FDDRQSGKLI | AVPSDITPQI | ARIVATRLRG | YPLPHRICYS | GRVLRHAELQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SGRSREIFQS | GVELIGLDSP | EADAEMVTMA | VEALKGLGFR | DFKIDLGHVG | FIRGIMTASG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LEVAVRNRLQ | EAIGKKDVSA | VRSILAESPL | SDAAKDELAA | LPRLFGGREV | LDEAGRVATN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DTSRRALDNI | SQVLDLLDIH | GVSDHLTIDL | GEVRGLDYHT | GLTFEGFVTG | MGEAVCSGGR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YDTLTARYGF | PAPATGFTFN | VLALLSALEK | RPDVEASKTR | DILIFNQQDD | RREALEIAQQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LRRRGYTTAR | DIIRRNFDDS | LDYARRMNIL | HMMVVGGDQC | GPDEVYLVRV | ADGQGQRIKK |
| 430 | |||||
| AEVFSERFSL | DAGPDKES |