P60283

PR
Gene name
rpoB
Protein name
DNA-directed RNA polymerase subunit beta
Names
PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta
Species
Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens)
KEGG Pathway
ppp:2546814
EC number
2.7.7.6: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

223-293 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P60283

Entry ID Method Resolution Chain Position Source
AF-P60283-F1 Predicted AlphaFoldDB

No variants for P60283

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P60283

No associated diseases with P60283

5 regional properties for P60283

Type Name Position InterPro Accession
domain DNA-directed RNA polymerase, subunit 2, hybrid-binding domain 596 - 994 IPR007120
conserved_site RNA polymerase, beta subunit, conserved site 832 - 844 IPR007121
domain RNA polymerase Rpb2, domain 7 996 - 1069 IPR007641
domain RNA polymerase Rpb2, domain 2 140 - 329 IPR007642
domain RNA polymerase Rpb2, domain 3 390 - 458 IPR007645

Functions

Description
EC Number 2.7.7.6 Nucleotidyltransferases
Subcellular Localization
  • Plastid, chloroplast
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity.

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
ribonucleoside binding Binding to a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose.

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKKIITLSAP PPSQFSFLSE FQFSLPELRQ IQFKSYYYFI YKNLISELNI FPEIFDLNQE
70 80 90 100 110 120
FQFELLNKEY KLIKPEKTTI KFHYNTYSSD LYVTCRLLRR KKKIEIQKQT IFIGSIPLID
130 140 150 160 170 180
YQSTFRINSV TRVIINQILR SPGIYYNSEL DHNGISIYTG TIISDWGGRL KLEIDSKTRI
190 200 210 220 230 240
WARISKKRKV SILVLLLAMG LTIKQILDSV CSSKIFLDFL KEKKKKKEHL QSTEDAMVEL
250 260 270 280 290 300
YKQLYYIGGD LLFSESIRKE LQKKFFQQRC ELGKIGRLNV NKKLSLDIPE NEFFLLPQDI
310 320 330 340 350 360
LAAIDYLIKI KFGIGTLDDI DHLKNRRIRS VADLLQDQLK LALIRLENSV RQVMRRTTKR
370 380 390 400 410 420
KRLLSPKNLI TQTPLIATFK EFFGSHPLSQ FLDQTNSLAE IVHKRRLSSL GPGGVTRRTA
430 440 450 460 470 480
GFQVRDIHFS HYTRICPIET SEGMNAGLIA SLAIHANVNN WGFLESPFYK ISKNVKEEKI
490 500 510 520 530 540
INLSAGEDEY YRIATGNCLA LDQGTQKIQI TPARYRQEFL AIAWEQIHLR SIYPLQYFSV
550 560 570 580 590 600
GVSLIPFLEH NDANRALMGS NMQRQAVPLI KLEKCIVGTG LESQVALDSG NVMITKQSEK
610 620 630 640 650 660
IMYTDGKKIS LLNNTNETVN THLIIYQRSN NSTCIHQKPQ VISKKFLKKG QVLTDGAAIL
670 680 690 700 710 720
KGELTLGKNI LVAYMPWEGY NFEDAILISE RLIYEDIYTS IHIERYEIES RNTNQGPEKI
730 740 750 760 770 780
TKEIPHLENS VLRHLDKNGL VIPGSWVETG DVLVGKLTPQ ETEESLRAPE GKLLQAIFGI
790 800 810 820 830 840
QVTNAKETCL KVPLNGKGRV IDVIWISKKE NSSNYEKIIH VYIAQKRKIQ VGDKVAGRHG
850 860 870 880 890 900
NKGIISKILP RQDMPYLQDG TPIDMVLSPL GVPSRMNVGQ IFECLLGLAG YFLGKHYRIT
910 920 930 940 950 960
PFDEKYEREA SRKLVFSELY KASKKTGNLW LFEPENPGKS RLLNGRTGEI FEQAVTVGKA
970 980 990 1000 1010 1020
YMLKLIHQVD DKIHARSSGP YALVTQQPLR GRSRRGGQRV GEMEVWALEG FGVAYILQEM
1030 1040 1050 1060 1070 1080
LTIKSDHIHA RYEVLGAIIT GEPIPKPKTA PESFLLLVRE LRSLSLELDH AVIFEKNLNI
KFKDV