P60036

PR
Gene name
yidC
Protein name
Membrane protein insertase YidC
Names
Foldase YidC, Membrane integrase YidC, Membrane protein YidC
Species
Porphyromonas gingivalis (strain ATCC BAA-308 / W83)
KEGG Pathway
pgi:PG_0526
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

2-105 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P60036

Entry ID Method Resolution Chain Position Source
AF-P60036-F1 Predicted AlphaFoldDB

No variants for P60036

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P60036

No associated diseases with P60036

3 regional properties for P60036

Type Name Position InterPro Accession
domain Membrane insertase YidC, N-terminal 2 - 362 IPR028053
domain Membrane insertase YidC/Oxa/ALB, C-terminal 375 - 577 IPR028055
domain Membrane insertase YidC/ALB, C-terminal 393 - 577 IPR047196

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
membrane insertase activity Binds transmembrane domain-containing proteins and mediates their integration into a membrane.

1 GO annotations of biological process

Name Definition
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDKNTVIGLV LIGLVIFGFS WLNRPDPQEI EAQRKAAIEA ARQDSIAKAE AELLAARTQG
70 80 90 100 110 120
ATPDSIKQAA GYNQYGLLAA ATAGAEEQVE LANGKIALKL STKGGAIREV LLRDYKTHDG
130 140 150 160 170 180
KPLYLFREGE SDFNLPLRTV DNRLVDTRDL YFSPISRTDS SVVMRLAVDS ASYLDLAYVL
190 200 210 220 230 240
LPDDYRLRMT VSGQNLQSLF PANMTMQDLE WSQRIRRQEK SWKFENQYTS IYYKYSGDEV
250 260 270 280 290 300
DRLSDSKQED KKTLEEPLHW VSFKDKYFAS VLVCDSYFEN NKLAQKTAAA GSDYLKNCTM
310 320 330 340 350 360
SATFPLDVRS GTKARFTFFF GPLKYNMLRA YDKGMKAEDN LDLDHLVYLG ASIFRWINRY
370 380 390 400 410 420
MIIPASTFLQ QYFSNWGLII LLLTLGIKLL ISPLAYKGYL SSAKMRLLRP QVQEINAKYP
430 440 450 460 470 480
GKDQESMMKR QSATMNLYRA AGAGPMSGCL PMLLQFPFLI AMYMYFPTTI DIRQQSFLWA
490 500 510 520 530 540
EDLSSYDAVF SWTADIPLLS QFYGNHVSLF CLLMSISNIL YIRYTMNQSD TGQEGMAMLK
550 560 570 580 590 600
WMPYITTVMF LFFFNQNASG LCYYYFLSSI ITVIQYMSSR FIINEEKLMA KLEANKTKPR
610 620
KKSKWMARLE EAQRQQEAMR RQQQKRK