P59972

PR
Gene name
BQ2027_MB1354C
Protein name
Uncharacterized protein Mb1354c
Names
Species
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-56 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P59972

Entry ID Method Resolution Chain Position Source
AF-P59972-F1 Predicted AlphaFoldDB

No variants for P59972

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P59972

No associated diseases with P59972

2 regional properties for P59972

Type Name Position InterPro Accession
domain Adenylyl cyclase class-3/4/guanylyl cyclase 325 - 530 IPR001054
domain HAMP domain 275 - 329 IPR003660

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
adenylate cyclase activity Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.

2 GO annotations of biological process

Name Definition
cyclic nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.
intracellular signal transduction The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPSEKATTRH LPGAVETLSP RTGRRPETPA YGSWLLGRVS ESPRMRRVRI QGMLTVAILV
70 80 90 100 110 120
TNVIGLIVGA MLLTVAFPKP SVILDAPHWV SFGIVPGYCV LAFILGTYWL TRQTARALRW
130 140 150 160 170 180
AIEERTPSHD EARSAFLVPL RVALAVLFLW GAAAALWTII YGLANRLFIP RFLFSMGVIG
190 200 210 220 230 240
VVAATSCYLL TEFALRPMAA QALEVGATPR SLVRGIVGRT MLVWLLCSGV PNVGVALTAI
250 260 270 280 290 300
FDDTFWELSN DQFMITVLIL WAPLLIFGFI LMWILAWLTA TPVRVVREAL NRVEQGDLSG
310 320 330 340 350 360
DLVVFDGTEL GELQRGFNRM VEGLRERERV RDLFGRHVGR EVAAAAERER PKLGGEERHV
370 380 390 400 410 420
AVVFVDIVGS TQLVTSRPAA EVVMLLNRFF TVIVDEVNHH RGLVNKFQGD ASLAVFGAPN
430 440 450 460 470 480
RLSHPEDAAL ATARAIADRL ASEMPECQAG IGVAAGQVVA GNVGAHERFE YTVIGEPVNE
490 500 510 520 530 540
AARLCELAKS YPSRLLASSQ TLRGASENEC ARWSLGETVT LRGHDQPIRL ASPVQQLQMP
550 560
AQSADIVGGA LGDHQTHTIY RGAHPTD