P59836

PR
Gene name
ftsK (HD_1476)
Protein name
DNA translocase FtsK
Names
Species
Haemophilus ducreyi (strain 35000HP / ATCC 700724)
KEGG Pathway
hdu:HD_1476
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

173-511 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P59836

Entry ID Method Resolution Chain Position Source
AF-P59836-F1 Predicted AlphaFoldDB

No variants for P59836

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P59836

No associated diseases with P59836

4 regional properties for P59836

Type Name Position InterPro Accession
domain FtsK domain 581 - 820 IPR002543
domain FtsK gamma domain 894 - 957 IPR018541
domain DNA translocase FtsK, 4TM region 20 - 180 IPR025199
domain FtsK alpha domain 473 - 573 IPR041027

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
  • Located at the septum
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

3 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
chromosome segregation The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTVIERFKSN LKGKQNLINF GFILIGLFGC YLLIAWASYS PLDNAWSTAS SVTHDTVLNK
70 80 90 100 110 120
TGKLGAWLID LLYAFLGNVA FVVPFVLFSF AIYALIFRIA EQWKWRNLLL QIGSFILLLI
130 140 150 160 170 180
GLSGIASVLL PNSAYYLAGG FVGGMLQSLL NGIIGQVGLL LLSTVLMSIG FYFCSGQLLF
190 200 210 220 230 240
SLGIQFYQWL FIKKPQSNTI LEAANPHLNA QNNETTKSIV ANPSENAHVD QLVTHENATE
250 260 270 280 290 300
QLTDVSAFTR PTIHGLKSSS TLNTDKTKYN QVNAQPLTDP MMFKIEKKVI LPKINMQHPE
310 320 330 340 350 360
NELTNLSMEQ TNSIDNLEIR LPKVHLNTAV TNPEIKTVEH HAQNRPLEMP TQIQPVFDQP
370 380 390 400 410 420
ITPTISLNVE DQPLDIESNE AQLAEEFAAA EQMRLANMEQ RAKAEGLEET FNQIITSPTL
430 440 450 460 470 480
TVSINESSEQ PTEKDLNPTH HDNGANYPKG YGKTLLHPLL QRNNVVEKPT TPLPTLELLA
490 500 510 520 530 540
KNPVQTQQIT EQEIFDTSHR LENALANYNV KATVEDVLVG PVVTRYEIKP AAGIKANKVT
550 560 570 580 590 600
ALANDLAREL MFKAIRITEV VPGKPYMGIE TPNTHRQTVW LRDVLDSEAF RHTQATLPMA
610 620 630 640 650 660
LGKDISGQPI VVDMAKMPHL LVAGQTGGGK SVGINTMILS LLFKLTPEQV RFIMIDPKVV
670 680 690 700 710 720
ELSVYNDIPH LLTPVVTDMK KAANALRWAV GEMERRYLLI SHLQVRNIEG YNDKIDQASA
730 740 750 760 770 780
MNFPIPDPTW RPADSIGQLP PPLTKLSYIV LIVDEFADLI MSAGKEVEEY IMRIAQKARA
790 800 810 820 830 840
VGIHLILATQ RPSTDVITGV IKANIPSRIA FTVASQIDSR TILDAGGAEA LLGRGDMLYS
850 860 870 880 890 900
ASGSPEIMRI HGAFMSDEEV QRIADNWRAR GKPQYLDSVV ASHEDENDSR TNTITELDPL
910 920 930 940 950
FDEIVAYVIE SGVTSISGIQ RRFSLGFNRA GRIIDQMEAQ AIISEPGKGG KREVLAR