Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P58991

Entry ID Method Resolution Chain Position Source
AF-P58991-F1 Predicted AlphaFoldDB

No variants for P58991

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P58991

No associated diseases with P58991

4 regional properties for P58991

Type Name Position InterPro Accession
domain Polyphosphate kinase middle domain 123 - 323 IPR024953
domain Polyphosphate kinase N-terminal domain 7 - 113 IPR025198
domain Polyphosphate kinase C-terminal domain 2 505 - 675 IPR025200
domain Polyphosphate kinase, C-terminal domain 1 333 - 496 IPR041108

Functions

Description
EC Number 2.7.4.1 Phosphotransferases with a phosphate group as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
polyphosphate kinase complex A protein complex that possesses polyphosphate kinase activity.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
polyphosphate kinase activity Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1).

2 GO annotations of biological process

Name Definition
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
polyphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSDPSLYINR ELSWLHFNRR VLDEAIRQDQ HPLIERVKFI AIFSSNLDEF FMIRVAGIEK
70 80 90 100 110 120
QVEAGIRKKT IDGLTPSEQL ERIRAEVIEQ LKLRNTCLYG DILPALAAEG ITFVHFADLP
130 140 150 160 170 180
EKEQAVLNAW FRKEIYPVLT PLAFDTGHPF PFMSNLSLNL AIELDEVEHG NLKFARVKVP
190 200 210 220 230 240
SVLPRLLKLN DIEGLGNDPS CMRFLWIEEL IQQNLGLLFP TMKIVQSHQF RIIRNADIEI
250 260 270 280 290 300
EEDEAGDLLQ TIEKGVRSRR YGNVVRLDIS PEMPDFVRQL LINNLEIEEK NVYEIDGALG
310 320 330 340 350 360
MSCLMELLDI DRPSLKDEPF IPFNMFEEQR NGDIFSAISS GDLLFYHPYD SFKPVVDFID
370 380 390 400 410 420
RAASDPDVLS IKQTLYRVGS NSPIVKALMK AAESGKQVAV LVELKARFDE ENNIGWARAL
430 440 450 460 470 480
EDVGAHVIYG LPGLKTHAKL TLVVRREPQG LKRYLHLGTG NYNPSTGKLY TDYSFFTDDE
490 500 510 520 530 540
LLAGEVSELF NALTGYFRYT GYRFLLVSPI NTRKRIIEMI EREIALARKS SGGRIIMKMN
550 560 570 580 590 600
SLVDPATIQA LYRASRAGVQ IDLVVRGICC LKPGIPGVSE NIRVISIIGR YLEHSRAYYF
610 620 630 640 650 660
ANGGSPELYL GSADIMPRNL DDRVETLFPV FDPSLVERVR NDLELQLSDN LKAWKIGPDG
670 680 690
NWTLVRNDAP KVNSQERFMK RRTQKKKTTG IKGRLGLN