P58814
Gene name |
apgM (PF1959) |
Protein name |
2,3-bisphosphoglycerate-independent phosphoglycerate mutase |
Names |
BPG-independent PGAM, Phosphoglyceromutase, aPGAM |
Species |
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) |
KEGG Pathway |
pfu:PF1959 |
EC number |
5.4.2.12: Phosphotransferases (phosphomutases) |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P58814
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P58814-F1 | Predicted | AlphaFoldDB |
No variants for P58814
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P58814 | |||||
No associated diseases with P58814
1 regional properties for P58814
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Metalloenzyme | 5 - 400 | IPR006124 |
Functions
| Description | ||
|---|---|---|
| EC Number | 5.4.2.12 | Phosphotransferases (phosphomutases) |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity | Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D glycerate; this reaction does not require the cofactor 2,3-bisphosphoglycerate. |
| metal ion binding | Binding to a metal ion. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| glycolytic process | The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKQRKGVLII | LDGLGDRPIK | ELGGKTPLEY | ANTPTMDYLA | KIGILGQQDP | IKPGQPAGSD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TAHLSIFGYD | PYKSYRGRGY | FEALGVGLEL | DEDDLAFRVN | FATLENGVIT | DRRAGRISTE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EAHELAKAIQ | ENVDIPVDFI | FKGATGHRAV | LVLKGMAEGY | KVGENDPHEA | GKPPHPFTWE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DEASKKVAEI | LEEFVKKAHE | VLDKHPINEK | RRKEGKPVAN | YLLIRGAGTY | PNIPMKFTEQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| WKVKAAAVVA | VALVKGVAKA | IGFDVYTPKG | ATGEYNTDEM | AKARKAVELL | KDYDFVFIHF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KPTDAAGHDN | NPKLKAELIE | RADRMIKYIV | DHVDLEDVVI | AITGDHSTPC | EVMNHSGDPV |
| 370 | 380 | 390 | 400 | 410 | |
| PLLIAGGGVR | ADYTEKFGER | EAMRGGLGRI | RGHDIVPIMM | DLMNRTEKFG | A |