P57996

PR
Gene name
secA1
Protein name
Protein translocase subunit SecA 1
Names
Species
Mycobacterium leprae (strain TN)
KEGG Pathway
mle:ML0779
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

837-915 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P57996

Entry ID Method Resolution Chain Position Source
AF-P57996-F1 Predicted AlphaFoldDB

No variants for P57996

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P57996

No associated diseases with P57996

No regional properties for P57996

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P57996

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLSKLLRLGE GRIVKRLKRV AEYVNTLSDN VEKLTDVELK AKTDEFKQRL ADEKNPESLD
70 80 90 100 110 120
DLLPEAFAVA REAAWRVLDQ RPFDVQVMGG AALHLGNVAE MKTGEGKTLT CVLPAYLNAL
130 140 150 160 170 180
AGKGVHIVTV NDYLAKRDSE WMGRVHRFLG LQVGVILASM TPDERRVAYN ADITYGTNNE
190 200 210 220 230 240
FGFDYLRDNM AHSLDDLVQR GHSYAIVDEV DSILIDEART PLIISGSADG ASNWYTEFAR
250 260 270 280 290 300
LVRLMDKDVH YEVDLRKRTV GVHEKGMEFV EDQLGIDNLY EVANSPLVSY LNNALKAKEL
310 320 330 340 350 360
FNRDKDYIVR DGEVLIVDEF TGRVLIGRRY NEGMHQAIEA KEHVEIKAEN QTLATITLQN
370 380 390 400 410 420
YFRLYDKLAG MTGTAQTEAA ELHEIYKLGV VAIPTNKPMI REDRSDLIYK TEEAKYMAVV
430 440 450 460 470 480
DDVAERYEKG QPVLIGTTSV ERSEYLSRQF TKRHIPHNVL NAKYHEQEAG IVAVAGRRGG
490 500 510 520 530 540
VTVATNMAGR GTDIVLGGNV DFLTDQRLRR RGLDPVETPD EYEQAWHSEL PKVKEEAGQE
550 560 570 580 590 600
AAEVIEAGGL YVLGTERHES RRIDNQLRGR SGRQGDPGES RFYLSLGDEL MRRFHGATLE
610 620 630 640 650 660
ALLTRLNLPD DVPIEAKMVT RAIKSAQTQV EQQNFEVRKN VLKYDEVMNQ QRKVIYAERR
670 680 690 700 710 720
RILEGESLQQ QALGMVRDVI TAYIDGATTD SYVEDWDLDA LWSALGTLYP VGIKHESLTH
730 740 750 760 770 780
ADEDSECDEL SRDELLEALL IDAQHAYAAR EAELAELAGE GAMRQLERNV LLNVVDRKWR
790 800 810 820 830 840
EHLYEMDYLK EGIGLRAMAQ RDPLVEYQRE GYDMFMAMLD GVKEESVGFL FNLAVEAVPA
850 860 870 880 890 900
SHVAPVEIPE GFTGLVADVE AIRPREEASS ALRTKDIDNE STGLTYSGPS EDGSTQVQLN
910 920 930
SGGGQKTPAG IPVGASRRER REAARRRGRG AKPSRSVKKR