Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P57873

Entry ID Method Resolution Chain Position Source
AF-P57873-F1 Predicted AlphaFoldDB

No variants for P57873

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P57873

No associated diseases with P57873

6 regional properties for P57873

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 333 - 502 IPR000795
domain Small GTP-binding protein domain 336 - 491 IPR005225
domain Translation initiation factor IF-2, N-terminal 258 - 308 IPR006847
domain Initiation factor 2 associated domain, bacterial 13 - 47 IPR013575
domain Translation initiation factor IF- 2, domain 3 609 - 723 IPR023115
domain Translation initiation factor IF-2, domain II 509 - 602 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTEDVKKADG AAPKKLSLQR RTKTTVSTTA GGKAKEVQVE VRKKRTVPTD AAQKAEEARL
70 80 90 100 110 120
KAKQEADRLA AEKAKKDAEE KARLEAEKAK QAKAEEAKKA QAVSAPTKAV DVEKEKRRAE
130 140 150 160 170 180
EAELRRKADE LARQKAEELA RKAAEEAKRY AELSEEDAEN ENSEDYADYH LTSTYAREAE
190 200 210 220 230 240
DEEARRKENR NRGGKNKVAK AKKGGREDES SKTERESNRR NQKDGKMGKG KHAKKGSALQ
250 260 270 280 290 300
QAFTKPAQAV NRDVVIGETI TVAELANKMA VKATEVIKTM MKMGAMATIN QVIDQETAQL
310 320 330 340 350 360
VAEEMGHKVI IRKENELEES VMSDRDVDAE LVTRAPVVTI MGHVDHGKTS LLDYIRKAKV
370 380 390 400 410 420
ASGEAGGITQ HIGAYHVETD GKMITFLDTP GHAAFTSMRA RGAKATDIVV LVVAADDGVM
430 440 450 460 470 480
PQTIEAIQHA KAAGVPIVVA VNKIDKPEAN PERVETELLQ HEVVAEKFGG DTQFVYVSAK
490 500 510 520 530 540
KGTGVDELLE AILLQSEVLE LTAVKDGMAT GVVIESYLDK GRGPVATILV QTGTLHRGDI
550 560 570 580 590 600
VLCGFEYGRV RAMRNENGKD VASAGPSIPV EVLGLSGVPA AGDEATVVRD EKKAREVALY
610 620 630 640 650 660
RQGKFREVKL ARQQKAKLEN MFTNMAEGDV AELNVIVKAD VQGSVEAICQ SLNELSTAEV
670 680 690 700 710 720
KVKVVGSGVG GITETDATLA AASNAIVLGF NVRADASARR IIESESIDLR YYSIIYELLN
730 740 750 760 770 780
EIKAAMSGML QPEFKQEIIG LAEVRDVFRH PKFGAIAGCM VTEGIVKRNN PIRVLRDNVV
790 800 810 820 830
IFEGELESLR RFKDDVAEVR NGMECGIGVK NYNDVKVGDQ IEVFEVVEIK RTI