P57101
Gene name |
hand2 (dhand) |
Protein name |
Heart- and neural crest derivatives-expressed protein 2 |
Names |
Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2, dHAND |
Species |
Xenopus laevis (African clawed frog) |
KEGG Pathway |
xla:373641 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P57101
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P57101-F1 | Predicted | AlphaFoldDB |
No variants for P57101
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P57101 | |||||
No associated diseases with P57101
1 regional properties for P57101
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Myc-type, basic helix-loop-helix (bHLH) domain | 92 - 150 | IPR011598 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| protein dimerization activity | The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSLVGGFPHH | PVVHHDGYPF | AAAAAAAASR | CHEENPYFHG | WLISHPEMSP | PDYSMAPSYS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PEYANGAAGL | DHSHYGGVPG | SGAGGLMQRP | VKRRGTANRK | ERRRTISINS | AFAELRECIP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NVPADTKLSK | IKTLRLATSY | IAYLMDLLAK | DDQNGETEAF | KAEIKKTDVK | EEKRKKELNE |
| 190 | 200 | ||||
| LLKSTVCSND | KKTKGRTGWP | QHVWALELKQ |