P56466
Gene name |
rho |
Protein name |
Transcription termination factor Rho |
Names |
ATP-dependent helicase Rho |
Species |
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) |
KEGG Pathway |
hpy:HP_0550 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P56466
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P56466-F1 | Predicted | AlphaFoldDB |
No variants for P56466
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P56466 | |||||
No associated diseases with P56466
6 regional properties for P56466
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain | 179 - 382 | IPR000194 |
| domain | AAA+ ATPase domain | 189 - 380 | IPR003593 |
| domain | Rho termination factor, N-terminal | 27 - 69 | IPR011112 |
| domain | Rho termination factor, RNA-binding domain | 70 - 145 | IPR011113 |
| domain | Cold shock domain | 74 - 140 | IPR011129 |
| domain | Transcription termination factor Rho, ATP binding domain | 176 - 423 | IPR041703 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP-dependent activity, acting on RNA | Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction. |
| helicase activity | Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix. |
| hydrolase activity | Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA-templated transcription termination | The completion of transcription: the RNA polymerase pauses, the RNA-DNA hybrid dissociates, followed by the release of the RNA polymerase from its DNA template. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNENAPTHKS | SHKVKTHTPV | SGYHIEDLRT | YPTEKLLEIA | NKLKVENPQE | FKRQDLMFEI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LKTQVTQGGY | ILFTGILEIM | PDGYGFLRGF | DGSFSDGHND | TYVSPSQIRR | FALRNGDIVT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GQVRSPKDQE | KYYALLKIEA | INYSPSDEIR | NRPLFDNLTP | LFPDEQIKLE | YEPTKVTGRM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LDLFSPVGKG | QRALIVAPPR | TGKTELMKEL | AQGITSNHPE | VELIILLVDE | RPEEVTDMQR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SVKGQVFSST | FDLPANNHIR | IAELVLERAK | RRVEMGKDVV | VLLDSITRLA | RAYNAVTPSS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GKVLSGGVDA | NALHRPKRFF | GAARNIEEGG | SLTIIATALI | ETGSRMDEVI | FEEFKGTGNS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EIVLARNIAD | RRIYPAFDIL | KSGTRKDNIL | LGKDRLTKVW | VLRNVMQQMD | DIEALSFVYS |
| 430 | |||||
| KMQQTKDNEE | FLNLMNEK |