P56185
Gene name |
rnj |
Protein name |
Ribonuclease J |
Names |
RNase J |
Species |
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) |
KEGG Pathway |
hpy:HP_1430 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for P56185
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 7PCR | X-ray | 275 A | A | 137-689 | PDB |
| AF-P56185-F1 | Predicted | AlphaFoldDB |
No variants for P56185
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P56185 | |||||
No associated diseases with P56185
1 regional properties for P56185
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Ribonuclease H domain | 1 - 142 | IPR002156 |
Functions
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| 5'-3' exoribonuclease activity | Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of an RNA molecule. |
| endoribonuclease activity | Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| zinc ion binding | Binding to a zinc ion (Zn). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| rRNA processing | Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTDNNQNNEN | HENSSENSKA | DEMRAGAFER | FTNRKKRFRE | NAQKNAEYSN | HEASSHHKKE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HRPNKKPNNH | HKQKHAKTRN | YAQEELDSNK | VEGVTEILHV | NERGTLGFHK | ELKKGVEANN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KIQVEHLNPH | YKMNLNSKAS | VKITPLGGLG | EIGGNMMVIE | TPKSAIVIDA | GMSFPKEGLF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GVDILIPDFS | YLHQIKDKIA | GIIITHAHED | HIGATPYLFK | ELQFPLYGTP | LSLGLIGSKF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DEHGLKKYRS | YFKIVEKRCP | ISVGEFIIEW | IHITHSIIDS | SALAIQTKAG | TIIHTGDFKI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DHTPVDNLPT | DLYRLAHYGE | KGVMLLLSDS | TNSHKSGTTP | SESTIAPAFD | TLFKEAQGRV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IMSTFSSNIH | RVYQAIQYGI | KYNRKIAVIG | RSMEKNLDIA | RELGYIHLPY | QSFIEANEVA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KYPDNEILIV | TTGSQGETMS | ALYRMATDEH | RHISIKPNDL | VIISAKAIPG | NEASVSAVLN |
| 490 | 500 | 510 | 520 | 530 | 540 |
| FLIKKEAKVA | YQEFDNIHVS | GHAAQEEQKL | MLRLIKPKFF | LPVHGEYNHV | ARHKQTAISC |
| 550 | 560 | 570 | 580 | 590 | 600 |
| GVPEKNIYLM | EDGDQVEVGP | AFIKKVGTIK | SGKSYVDNQS | NLSIDTSIVQ | QREEVASAGV |
| 610 | 620 | 630 | 640 | 650 | 660 |
| FVATIFVNKN | KQALLESSQF | SSLGLVGFKD | EKPLIKEIQG | GLEVLLKSSN | AEILNNPKKL |
| 670 | 680 | ||||
| EDHTRNFIRK | ALFKKFRKYP | AIICHAHSF |