AiPD: Autoinhibited Protein Database

P56180

Gene name	TPTE
Protein name	Putative tyrosine-protein phosphatase TPTE
Names	Cancer/testis antigen 44, CT44, Transmembrane phosphatase with tensin homology, Tumor antigen BJ-HCC-5
Species	Homo sapiens (Human)
KEGG Pathway	hsa:7179
EC number	3.1.3.48: Phosphoric monoester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-67 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

1-67 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for P56180

Entry ID	Method	Resolution	Chain	Position	Source
AF-P56180-F1	Predicted				AlphaFoldDB

1277 variants for P56180

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
TCGA novel	1	M>?	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	3	E>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409855169 rs1255945263	3	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs1365331896 CA409855178	4	S>C		No	ClinGen gnomAD
TCGA novel	4	S>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1288786195 CA409855198	4	S>R		No	ClinGen gnomAD
TCGA novel	4	S>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs780937290 CA9978571	5	P>S		No	ClinGen ExAC TOPMed gnomAD
rs1334658836 CA409855206	6	D>H		No	ClinGen gnomAD
TCGA novel	6	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9978569 rs149877959	7	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs149877959 CA409855215	7	P>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs768447995 CA9978570	7	P>S		No	ClinGen ExAC TOPMed gnomAD
CA409855221 rs1302263000	8	T>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1287691911 CA409855216	8	T>P		No	ClinGen TOPMed
TCGA novel	9	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9978566 rs750881399	10	L>M		No	ClinGen ExAC TOPMed
CA409855237 rs139096194	11	A>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	11	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs139096194 CA9978565	11	A>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA9978561 rs760917517	12	G>A		No	ClinGen ExAC gnomAD
TCGA novel	12	G>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9978563 CA9978562 rs764249659	12	G>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC TOPMed gnomAD NCI-TCGA
CA9978558 rs762859803	13	V>A		No	ClinGen ExAC gnomAD
CA409855242 rs150733676	13	V>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs762859803 CA409855244	13	V>G		No	ClinGen ExAC gnomAD
CA9978560 rs150733676	13	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA9978559 rs150733676	13	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs761362233 CA9978555	14	I>T		No	ClinGen ExAC gnomAD
rs371889505 CA9978556	14	I>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA9978554 rs368747576	15	I>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1350649577 CA409855259	16	E>A		No	ClinGen gnomAD
TCGA novel	16	E>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	17	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	17	L>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9978550 rs141265676	18	G>D	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
CA9978551 rs746642375	18	G>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	18	G>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	19	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1488053137 CA409855275	19	P>S		No	ClinGen TOPMed
CA9978547 rs757804219	20	N>S		No	ClinGen ExAC TOPMed gnomAD
CA9978546 rs757804219	20	N>T		No	ClinGen ExAC TOPMed gnomAD
rs1298620209 CA409855289	21	D>A		No	ClinGen gnomAD
TCGA novel	21	D>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs780491487 CA9978494	23	P>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs753701324 CA9978492	24	Q>R		No	ClinGen ExAC gnomAD
CA409855329 rs1280255523	25	T>A		No	ClinGen gnomAD
TCGA novel	25	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409855327 rs1280255523	25	T>P		No	ClinGen gnomAD
CA317685791 rs1034867365	25	T>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA409855334 rs1334222473	26	S>C		No	ClinGen gnomAD
TCGA novel	26	S>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1305293992 CA409855335	26	S>N		No	ClinGen TOPMed gnomAD
TCGA novel	26	S>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1305293992 CA409855336	26	S>T		No	ClinGen TOPMed gnomAD
TCGA novel	27	E>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	29	K>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409855360 rs1365439037	29	K>R		No	ClinGen gnomAD
TCGA novel	30	G>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	31	A>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs752616094 CA9978489	31	A>T		No	ClinGen ExAC gnomAD
CA9978488 rs767031383	31	A>V		No	ClinGen ExAC gnomAD
CA409855375 rs1424875846	32	T>A		No	ClinGen TOPMed
TCGA novel	33	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs751216471 CA9978486	33	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA9978484 rs143765390	35	A>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs143765390 CA9978485	35	A>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA409855402 rs1568960272	36	P>R		No	ClinGen Ensembl
rs773587467 CA9978483	36	P>S		No	ClinGen ExAC TOPMed gnomAD
CA9978481 rs368032413	37	A>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA9978482 rs770187693	37	A>T		No	ClinGen ExAC gnomAD
CA9978480 rs368032413	37	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA409855411 rs1362043376	38	K>R		No	ClinGen Ensembl
CA409855417 rs1398151563	39	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs1223320545 CA409855428	40	S>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA409855423 rs1342451134	40	S>R		No	ClinGen TOPMed
TCGA novel	40	S>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs776319606 CA9978426	41	P>L		No	ClinGen ExAC gnomAD
rs1353676205 CA409855446	41	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
TCGA novel	41	P>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs573430979 CA9978423	42	H>L		No	ClinGen 1000Genomes ExAC gnomAD
rs553549668 CA9978421	42	H>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs573430979 CA9978422	42	H>R		No	ClinGen 1000Genomes ExAC gnomAD
rs372593053 CA9978424	42	H>Y		No	ClinGen ESP ExAC gnomAD
CA9978420 rs191128347	43	T>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	43	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs753570153 CA409855454	43	T>K		No	ClinGen ExAC TOPMed gnomAD
CA9978419 rs191128347	43	T>P		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs753570153 CA9978418	43	T>R		No	ClinGen ExAC TOPMed gnomAD
CA9978417 rs764341151	44	S>G		No	ClinGen ExAC TOPMed gnomAD
rs1481112615 CA409855465	45	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA409855463 rs1481112615	45	E>Q		No	ClinGen TOPMed gnomAD
rs1251062330 CA409855476	46	F>C		No	ClinGen gnomAD
rs756601993 CA9978416	46	F>L		No	ClinGen ExAC gnomAD
CA409855484 rs1362128268	47	K>N		No	ClinGen gnomAD
TCGA novel	48	G>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs753249051 CA9978415	50	A>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA409855499 rs753249051	50	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA409855504 rs759630343	51	R>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA9978413 rs759630343	51	R>Q	Variant assessed as Somatic; 0.0001386 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs375208494 CA9978414	51	R>W		No	ClinGen ESP ExAC TOPMed gnomAD
CA409855511 rs1391589964	52	V>G		No	ClinGen TOPMed gnomAD
TCGA novel	52	V>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	53	S>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409855520 rs1568961317	54	P>A		No	ClinGen Ensembl
rs1380800742 CA409855522	54	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA409855519 rs1568961317	54	P>T		No	ClinGen Ensembl
CA409855524 rs766581855	55	I>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs766581855 CA409855525	55	I>L		No	ClinGen ExAC TOPMed gnomAD
CA409855527 rs1600873450	55	I>T		No	ClinGen Ensembl
rs766581855 CA9978410	55	I>V		No	ClinGen ExAC TOPMed gnomAD
CA409855531 rs1406559176	56	S>G		No	ClinGen TOPMed gnomAD
TCGA novel	56	S>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409855530 rs1406559176	56	S>R		No	ClinGen TOPMed gnomAD
rs1034839443 CA317686205	56	S>T		No	ClinGen TOPMed
rs1366027684 CA409855539	57	E>*		No	ClinGen gnomAD
TCGA novel	57	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs773542326 CA9978408	58	S>G		No	ClinGen ExAC gnomAD
rs1422716916 CA409855547	58	S>N		No	ClinGen gnomAD
CA9978409 rs773542326	58	S>R		No	ClinGen ExAC gnomAD
rs1184937704 CA409855574	59	V>A		No	ClinGen gnomAD
rs762316652 CA9978358	59	V>M		No	ClinGen ExAC gnomAD
rs1262132371 CA409855584	61	A>S		No	ClinGen TOPMed gnomAD
rs1262132371 CA409855582	61	A>T		No	ClinGen TOPMed gnomAD
CA9978355 rs138821247	62	R>*		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs578173995 CA9978354	62	R>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA9978353 rs578173995	62	R>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA9978349 rs746405212	64	S>F		No	ClinGen ExAC
rs758980001 CA409855597	64	S>P		No	ClinGen ExAC gnomAD
CA9978350 rs758980001	64	S>T		No	ClinGen ExAC gnomAD
CA409855603 rs1600890037	65	K>T		No	ClinGen Ensembl
rs757387568 CA9978346	67	E>G		No	ClinGen ExAC gnomAD
CA9978345 rs111657679	68	V>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs111657679 CA9978344	68	V>D		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA9978343 rs141287188	69	E>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs751388245 CA9978342	70	D>G		No	ClinGen ExAC TOPMed gnomAD
rs1455342655 CA409855635	70	D>H		No	ClinGen TOPMed
rs766186396 CA9978341	71	A>G		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	72	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	73	N>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9978340 rs762915125	75	A>G		No	ClinGen ExAC TOPMed gnomAD
CA409855672 rs762915125	75	A>V		No	ClinGen ExAC TOPMed gnomAD
rs773330398 CA9978339	76	S>L		No	ClinGen ExAC TOPMed gnomAD
rs761414041 CA9978337	77	Y>N		No	ClinGen ExAC
CA409855680 rs1184916247	77	Y>S		No	ClinGen gnomAD
TCGA novel	78	D>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409855689 rs1439242294	78	D>G		No	ClinGen gnomAD
rs1217933055 CA409817413	79	S>I		No	ClinGen gnomAD
CA9978302 CA9978303 rs750266849	79	S>R		No	ClinGen ExAC gnomAD
CA9978301 rs778954637	80	K>E		No	ClinGen ExAC gnomAD
TCGA novel	80	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs757230899 CA9978300	80	K>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs757230899 CA409817418	80	K>T		No	ClinGen ExAC TOPMed gnomAD
CA409817422 rs763651497	81	I>F		No	ClinGen ExAC TOPMed gnomAD
CA9978298 rs763651497	81	I>L		No	ClinGen ExAC TOPMed gnomAD
rs763651497 CA9978299	81	I>V		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	83	K>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs760172691 CA409817444	84	I>F		No	ClinGen ExAC TOPMed gnomAD
CA9978297 rs760172691	84	I>V		No	ClinGen ExAC TOPMed gnomAD
CA409817451 rs1396717686	85	V>A		No	ClinGen gnomAD
CA317598589 rs201974711	85	V>L		No	ClinGen 1000Genomes ExAC gnomAD
CA9978296 rs201974711	85	V>M		No	ClinGen 1000Genomes ExAC gnomAD
CA317598591 rs947422268	86	H>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs1452854273 CA409817463	87	S>*		No	ClinGen TOPMed
rs146617486 CA409817467	88	I>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs146617486 CA409817466	88	I>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA317598598 rs774725086	88	I>M		No	ClinGen ExAC TOPMed
rs146617486 CA9978294	88	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA9978292 rs771322142	89	V>A		No	ClinGen ExAC gnomAD
TCGA novel	89	V>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs773649955 CA9978290	90	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1215057188 CA409817485	91	S>C		No	ClinGen TOPMed
TCGA novel	91	S>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1600900637 CA409817489	92	F>V		No	ClinGen Ensembl
rs1273030549 CA409817499	93	A>V		No	ClinGen TOPMed
CA409817508 rs1402199095	94	F>L		No	ClinGen gnomAD
CA9978286 rs769031865	95	G>R		No	ClinGen ExAC gnomAD
CA9978285 rs747276081	95	G>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1224059298 CA409817524	96	L>I		No	ClinGen TOPMed gnomAD
TCGA novel	96	L>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1224059298 CA409817525	96	L>V		No	ClinGen TOPMed gnomAD
rs746535199 CA9978236	98	G>E		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	99	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9978235 rs779643234	99	V>I		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	100	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9978234 rs757957068	100	F>S		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	101	L>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA317599077 rs982997525	101	L>V		No	ClinGen TOPMed
CA9978233 rs558436767	102	V>D	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA gnomAD
TCGA novel	102	V>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1161510768 CA409817564	103	L>V		No	ClinGen gnomAD
CA409817572 rs1411632690	104	L>P		No	ClinGen TOPMed gnomAD
CA9978230 rs370278673	104	L>V		No	ClinGen ESP ExAC
TCGA novel	105	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs764715975 CA9978228	106	V>A	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs764715975 CA409817585	106	V>D		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	106	V>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	107	T>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs762040852 CA409817591	107	T>N		No	ClinGen ExAC TOPMed gnomAD
rs762040852 CA9978227	107	T>S		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	108	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs140748372 CA9978226	108	L>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA409817597 rs1453206794	109	I>L		No	ClinGen TOPMed
TCGA novel	110	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409817611 rs1482810842	111	A>P		No	ClinGen TOPMed
TCGA novel	111	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	112	D>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs139396383 CA9978223	112	D>N		No	ClinGen ESP ExAC TOPMed gnomAD
rs1440973763 CA409817619	112	D>V		No	ClinGen gnomAD
TCGA novel	115	F>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	115	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	115	F>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1333264546 CA409817647	116	T>N		No	ClinGen TOPMed
CA409817648 rs1333264546	116	T>S		No	ClinGen TOPMed
rs1385045078 CA409817660	118	S>N		No	ClinGen gnomAD
CA9978218 rs768601508	119	K>E		No	ClinGen ExAC gnomAD
TCGA novel	119	K>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9978217 rs746988740	119	K>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
TCGA novel	120	L>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	120	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409817676 rs1388190275	120	L>R		No	ClinGen gnomAD
rs556974504 CA9978215	121	Y>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs556974504 CA9978216	121	Y>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs745506111 CA9978214	122	I>T		No	ClinGen ExAC gnomAD
rs1309434820 CA409817684	122	I>V		No	ClinGen TOPMed
CA9978212 rs537044433	123	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA gnomAD
CA9978213 rs778635152	123	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1022480037 CA317599167 TCGA novel	124	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen TOPMed gnomAD NCI-TCGA
CA317599160 rs181214187	124	L>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA9978211 rs181214187	124	L>W		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	125	E>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409817709 rs1170535192	126	Y>C		No	ClinGen TOPMed
rs148393004 CA9978209	127	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	127	R>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs113140892 CA9978207	127	R>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs113140892 CA9978208	127	R>P		No	ClinGen ESP ExAC TOPMed gnomAD
rs148393004 CA9978210	127	R>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	128	S>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9978205 rs751664954	128	S>C		No	ClinGen ExAC gnomAD
CA9978206 rs751664954	128	S>F		No	ClinGen ExAC gnomAD
rs761546855 CA9978203	129	I>T		No	ClinGen ExAC gnomAD
CA9978204 rs371357693	129	I>V		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	130	S>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs776380657 CA9978202	130	S>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA409817737 rs1309223423	132	A>D		No	ClinGen TOPMed gnomAD
CA409817736 rs1230908495	132	A>P		No	ClinGen TOPMed gnomAD
CA409817739 rs1309223423	132	A>V		No	ClinGen TOPMed gnomAD
CA9978200 rs760594483	133	I>S		No	ClinGen ExAC gnomAD
CA409817741 rs1299836157	133	I>V		No	ClinGen TOPMed gnomAD
CA9978199 rs548871257	134	A>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs745398858 CA9978197	135	L>V		No	ClinGen ExAC TOPMed gnomAD
CA9978196 rs778385277	136	F>C		No	ClinGen ExAC gnomAD
CA409817758 rs1454820172	136	F>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
TCGA novel	137	F>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs58884111 CA317599214	138	L>F		No	ClinGen ExAC gnomAD
CA9978194 rs748984984	138	L>H		No	ClinGen ExAC
CA9978195 rs58884111	138	L>I		No	ClinGen ExAC gnomAD
rs1349214784	138	L>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409817781 rs756602065 CA9978192	139	M>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC TOPMed gnomAD NCI-TCGA
CA409817780 rs1169843624	139	M>R		No	ClinGen gnomAD
rs1375298987 CA409817776	139	M>V		No	ClinGen TOPMed gnomAD
TCGA novel	140	D>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9978191 rs748657909	140	D>N		No	ClinGen ExAC gnomAD
rs781723934 CA9978190	140	D>V		No	ClinGen ExAC gnomAD
TCGA novel	140	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409817793 rs1359876033	141	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs754952718 CA9978189	141	V>I		No	ClinGen ExAC gnomAD
rs956530051 CA409817794	142	L>F		No	ClinGen TOPMed gnomAD
CA317599248 rs766470602	142	L>H		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	142	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs766470602 CA9978187	142	L>P		No	ClinGen ExAC TOPMed gnomAD
rs956530051 CA317599247	142	L>V		No	ClinGen TOPMed gnomAD
CA409817799 rs1421061378	143	L>F		No	ClinGen gnomAD
CA9978185 rs534971558	144	R>*		No	ClinGen 1000Genomes ExAC gnomAD
TCGA novel	144	R>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
VAR_036516 CA9978184 rs144333919	144	R>Q	a breast cancer sample; somatic mutation [UniProt]	No	ClinGen UniProt ESP ExAC TOPMed dbSNP
TCGA novel	145	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1227662906 CA409817806	145	V>I		No	ClinGen TOPMed gnomAD
CA409817807 rs1227662906	145	V>L		No	ClinGen TOPMed gnomAD
rs117465555 CA9978182	147	V>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs117465555 CA409817821	147	V>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	148	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9978181 rs775235250	149	R>G		No	ClinGen ExAC gnomAD
CA9978180 rs767516117	149	R>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
TCGA novel	150	R>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	150	R>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	150	R>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	151	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9978118 rs751331487	151	Q>K		No	ClinGen ExAC gnomAD
TCGA novel	151	Q>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	152	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs545685203 CA9978116	152	Q>R		No	ClinGen 1000Genomes ExAC gnomAD
TCGA novel	153	Y>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9978113 rs764836489	153	Y>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs764836489 CA9978114	153	Y>F		No	ClinGen ExAC gnomAD
TCGA novel	154	F>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1360133131 CA409817880	154	F>S		No	ClinGen TOPMed
rs753473286 CA9978111	155	S>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
TCGA novel	155	S>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9978108 rs767922290 CA9978107	156	D>E		No	ClinGen ExAC TOPMed gnomAD
CA9978110 rs763679653	156	D>H		No	ClinGen ExAC TOPMed gnomAD
CA409817899 rs760019807 CA9978106	157	L>F		No	ClinGen ExAC gnomAD
CA409817895 rs1344965268	157	L>V		No	ClinGen TOPMed gnomAD
rs576586650 CA9978105	158	F>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1365376661 CA409817909	159	N>D		No	ClinGen gnomAD
CA409817911 rs749339905	159	N>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	159	N>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs749339905 CA9978103	159	N>T		No	ClinGen ExAC TOPMed gnomAD
CA9978100 rs748420771	161	L>*		No	ClinGen ExAC gnomAD
CA9978101 rs769938767	161	L>V		No	ClinGen ExAC gnomAD
CA9978098 rs758335031	162	D>E		No	ClinGen ExAC TOPMed gnomAD
rs779972291 CA9978099	162	D>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA9978097 rs745734162	163	T>A		No	ClinGen ExAC TOPMed gnomAD
rs779009659 CA9978096	163	T>I		No	ClinGen ExAC gnomAD
TCGA novel	163	T>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs974928235 CA317601818	164	A>S		No	ClinGen TOPMed
CA9978094 rs753321553	165	I>T		No	ClinGen ExAC TOPMed gnomAD
CA9978095 rs756744570	165	I>V		No	ClinGen ExAC gnomAD
CA9978091 rs752408703	166	I>F		No	ClinGen ExAC TOPMed gnomAD
rs372056580 CA9978090	166	I>T		No	ClinGen ESP ExAC gnomAD
rs752408703 CA9978092	166	I>V		No	ClinGen ExAC TOPMed gnomAD
rs1600916686 CA409817952	167	V>L		No	ClinGen Ensembl
rs759895278 CA9978089	168	I>L		No	ClinGen ExAC gnomAD
TCGA novel	168	I>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409817959 rs1336869572	168	I>T		No	ClinGen TOPMed
CA409817963 rs556698994	169	L>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs556698994 CA9978088	169	L>I	Variant assessed as Somatic; 0.0004164 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	170	L>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs769964335 CA9978084	172	V>D		No	ClinGen ExAC TOPMed
rs773134113 CA9978086	172	V>F		No	ClinGen ExAC TOPMed gnomAD
rs773134113 CA9978085	172	V>I		No	ClinGen ExAC TOPMed gnomAD
rs1293322799 CA409817983	173	D>E		No	ClinGen TOPMed
rs771936846 CA9978082	173	D>G		No	ClinGen ExAC TOPMed gnomAD
CA9978083 rs748367707	173	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA9978081 rs771936846	173	D>V		No	ClinGen ExAC TOPMed gnomAD
rs778872276 CA9978079	174	V>A		No	ClinGen ExAC gnomAD
CA409817986 rs745681114	174	V>F		No	ClinGen ExAC gnomAD
rs745681114 CA9978080	174	V>I		No	ClinGen ExAC gnomAD
CA409817991 rs1430389765	175	V>A	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs755683317 CA9978075	175	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs755683317 CA9978076	175	V>L		No	ClinGen ExAC TOPMed gnomAD
rs1426895138 CA409817998	176	Y>*		No	ClinGen gnomAD
rs752275988 CA9978073	176	Y>H		No	ClinGen ExAC gnomAD
CA9978072 rs755284879	177	I>F		No	ClinGen ExAC gnomAD
CA9978071 rs755284879	177	I>L		No	ClinGen ExAC gnomAD
CA409818001 rs1182728342	177	I>N		No	ClinGen gnomAD
TCGA novel	178	F>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1255908843 CA409818009	178	F>S		No	ClinGen gnomAD
TCGA novel	178	F>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409818008 rs1255908843	178	F>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
TCGA novel	179	F>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409818024 rs1194972976	180	D>Y		No	ClinGen TOPMed
rs763345667 CA9978066	181	I>T		No	ClinGen ExAC TOPMed gnomAD
rs367969920 CA9978067	181	I>V		No	ClinGen ESP ExAC gnomAD
CA409818039 rs750996733	182	K>M		No	ClinGen ExAC TOPMed gnomAD
rs750996733 CA9978065	182	K>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	182	K>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1202420817 CA409818044	183	L>*		No	ClinGen gnomAD
rs761998205 CA9978063	183	L>F		No	ClinGen ExAC TOPMed gnomAD
rs776946246 CA9978061	184	L>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs968847494 CA9978058	185	R>G		No	ClinGen TOPMed
CA9978056 rs773997628	185	R>K		No	ClinGen ExAC gnomAD
CA9978055 rs770820681	185	R>S		No	ClinGen ExAC gnomAD
CA9978057 rs773997628	185	R>T		No	ClinGen ExAC gnomAD
CA409818057 rs1410316854	186	N>D		No	ClinGen gnomAD
TCGA novel	186	N>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9978054 rs749182650	186	N>S		No	ClinGen ExAC gnomAD
CA317601996 rs878915635	187	I>M		No	ClinGen gnomAD
TCGA novel	187	I>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9978052 rs769232775	187	I>V		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	188	P>=	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	188	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs747676071 CA9978051	188	P>R		No	ClinGen ExAC gnomAD
TCGA novel	188	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	189	R>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9978049 rs138088406	189	R>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs1326665432 CA409818090	189	R>S		No	ClinGen TOPMed
CA9978050 rs138088406	189	R>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA409818095 rs1255334410	190	W>*		No	ClinGen gnomAD
rs1483486377 CA409818093	190	W>R		No	ClinGen gnomAD
rs751838173 CA9977994	191	T>A		No	ClinGen ExAC TOPMed gnomAD
CA9977993 rs765013039	191	T>I		No	ClinGen ExAC TOPMed gnomAD
rs1229365937 CA409818106	192	H>D		No	ClinGen gnomAD
CA409818105 rs1229365937	192	H>N		No	ClinGen gnomAD
TCGA novel	192	H>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1364743880 CA409818109	192	H>R		No	ClinGen gnomAD
rs1229365937 CA409818107	192	H>Y		No	ClinGen gnomAD
TCGA novel	193	L>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977991 rs776502829	194	L>F		No	ClinGen ExAC TOPMed gnomAD
rs546847748 CA9977990	194	L>H		No	ClinGen 1000Genomes ExAC gnomAD
rs546847748 CA409818122	194	L>P		No	ClinGen 1000Genomes ExAC gnomAD
rs776502829 CA409818121	194	L>V		No	ClinGen ExAC TOPMed gnomAD
CA9977988 rs775040644	195	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA9977987 rs1810856	195	R>L		No	ClinGen ExAC TOPMed gnomAD
CA9977986 rs1810856 VAR_057347	195	R>Q		No	ClinGen UniProt ExAC TOPMed dbSNP gnomAD
rs771358886 CA9977984	196	L>P		No	ClinGen ExAC gnomAD
rs774147763 CA9977985	196	L>V		No	ClinGen ExAC gnomAD
CA9977982 rs147014138	198	R>*		No	ClinGen ESP ExAC TOPMed gnomAD
CA9977983 rs147014138	198	R>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs756616733 CA9977981	198	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs796693040 CA409818138	199	L>F		No	ClinGen TOPMed gnomAD
TCGA novel	199	L>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA317602813 rs796693040	199	L>I		No	ClinGen TOPMed gnomAD
rs1368265719 CA409818141	199	L>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA409818137 rs796693040	199	L>V		No	ClinGen TOPMed gnomAD
CA9977980 rs748655283	200	I>T		No	ClinGen ExAC gnomAD
rs781320323 CA9977979	201	I>N		No	ClinGen ExAC gnomAD
rs1447008838 CA409818154	202	L>M		No	ClinGen TOPMed
rs757005766 CA9977973	204	R>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1160110233 CA409818177	205	I>M		No	ClinGen gnomAD
TCGA novel	205	I>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1263464205 CA409818175	205	I>T		No	ClinGen TOPMed
rs753599184 CA9977972	205	I>V		No	ClinGen ExAC gnomAD
CA409818183 rs1293093836	206	F>S		No	ClinGen TOPMed gnomAD
CA409818181 rs1293093836	206	F>Y		No	ClinGen TOPMed gnomAD
TCGA novel	207	H>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs148306452 CA9977971	207	H>L		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	207	H>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs148306452 CA9977970	207	H>R		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	207	H>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409818195 rs1309227089	208	L>R		No	ClinGen gnomAD
TCGA novel	208	L>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	209	F>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs766982471 CA9977968	209	F>L		No	ClinGen ExAC gnomAD
rs550676604 CA9977966	210	H>L		No	ClinGen 1000Genomes ExAC gnomAD
CA9977967 rs759128119	210	H>N		No	ClinGen ExAC TOPMed gnomAD
CA9977965 rs143230290	211	Q>*		No	ClinGen ESP ExAC TOPMed gnomAD
rs143230290 CA409818211	211	Q>E		No	ClinGen ESP ExAC TOPMed gnomAD
rs141319407 CA9977964	211	Q>P		No	ClinGen ExAC TOPMed gnomAD
rs773692291 CA9977963	212	K>E		No	ClinGen ExAC gnomAD
rs770116757 CA9977962	212	K>N		No	ClinGen ExAC TOPMed gnomAD
rs1181453637 CA409818223	213	R>*		No	ClinGen gnomAD
rs1568981005	213	R>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	213	R>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	213	R>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs748685215 CA9977961	213	R>S		No	ClinGen ExAC TOPMed gnomAD
rs1271034419 CA409818238	215	L>F		No	ClinGen gnomAD
CA409818240 rs1211817707	215	L>P		No	ClinGen TOPMed gnomAD
rs1211817707 CA409818241	215	L>R		No	ClinGen TOPMed gnomAD
CA409818242 rs1568981033	216	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
CA409818256 CA409818257 rs1357325155	217	K>N		No	ClinGen TOPMed gnomAD
CA409818260 rs781556068	218	L>Q		No	ClinGen ExAC gnomAD
CA9977960 rs781556068	218	L>R		No	ClinGen ExAC gnomAD
rs1352783639 CA409818263	219	I>L		No	ClinGen gnomAD
CA9977957 rs780146856	219	I>M		No	ClinGen ExAC gnomAD
CA409818272 rs1216098135	220	R>I		No	ClinGen gnomAD
CA409818270 rs1216098135	220	R>K		No	ClinGen gnomAD
rs758595440 CA9977956	220	R>S		No	ClinGen ExAC gnomAD
CA9977954 rs1243361386	221	R>G		No	ClinGen TOPMed
rs1333426167 CA409818275	221	R>K		No	ClinGen TOPMed gnomAD
rs1450717329 CA409818279	221	R>S		No	ClinGen TOPMed
CA409818276 rs1333426167	221	R>T		No	ClinGen TOPMed gnomAD
TCGA novel rs1273898804	222	R>=	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs530503790 CA409818282	222	R>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs530503790 CA9977948	222	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs76723236 CA9977949	222	R>W		No	ClinGen ExAC TOPMed
TCGA novel	223	V>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409818293 rs1212492438	223	V>I		No	ClinGen gnomAD
CA409818304 rs1381007288	224	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
TCGA novel	225	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs760125022 CA9977884	226	N>D		No	ClinGen ExAC gnomAD
CA9977885 rs760125022	226	N>H		No	ClinGen ExAC gnomAD
CA409818320 rs1353499643	227	K>E		No	ClinGen gnomAD
rs771102738 CA9977882	227	K>N		No	ClinGen ExAC gnomAD
TCGA novel	228	R>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	228	R>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs749470071 CA9977880	228	R>S		No	ClinGen ExAC TOPMed gnomAD
rs1810540 CA9977878	229	R>*		No	ClinGen ExAC TOPMed gnomAD
CA409818334 rs566493792	229	R>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs566493792 CA9977877	229	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	230	Y>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs745876374 CA9977874	230	Y>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA409818345 rs1185018439	231	T>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA409818346 rs1185018439	231	T>R		No	ClinGen gnomAD
rs1256015892 CA409818344	231	T>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA409818352 rs1460256558	232	R>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA9977871 rs756795446	232	R>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs777423996 CA409818356	233	D>A		No	ClinGen ExAC gnomAD
TCGA novel	233	D>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs753370600 CA9977870	233	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs777423996 CA9977869	233	D>V		No	ClinGen ExAC gnomAD
CA9977867 rs753025946	234	G>*		No	ClinGen ExAC gnomAD
TCGA novel	234	G>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs767922064 CA9977866	235	F>C		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	236	D>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	236	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409818372 rs1332496921	236	D>Y		No	ClinGen gnomAD
CA9977864 rs752179158	237	L>I		No	ClinGen ExAC gnomAD
CA9977863 rs766306733	237	L>P		No	ClinGen ExAC gnomAD
CA9977865 rs752179158	237	L>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA409818388 rs773520801	238	D>E		No	ClinGen ExAC TOPMed gnomAD
CA9977862 rs763108699	238	D>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1440212412 CA409818393	239	L>P		No	ClinGen TOPMed gnomAD
CA409818394 rs1440212412	239	L>R		No	ClinGen TOPMed gnomAD
CA409818400 rs1319030312	240	T>I		No	ClinGen TOPMed
rs1351818147 CA409818395	240	T>P		No	ClinGen gnomAD
rs1351818147 CA409818397	240	T>S		No	ClinGen gnomAD
CA9977859 rs770155216	241	Y>*		No	ClinGen ExAC
rs112131828 CA9977857	241	Y>*		No	ClinGen ESP ExAC TOPMed gnomAD
CA9977860 rs770172879	241	Y>H		No	ClinGen ExAC gnomAD
rs113857613 CA9977854	242	V>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs113857613 CA9977855	242	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA9977856 rs113857613	242	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	243	T>=	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	243	T>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977852 rs748824726	243	T>R		No	ClinGen ExAC gnomAD
CA9977853 rs770294722	243	T>S		No	ClinGen ExAC TOPMed gnomAD
rs755738282 CA9977850	244	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA9977778 rs376901636	245	R>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA9977780 rs376901636	245	R>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs371995616 CA9977776	245	R>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs371995616 CA9977775	245	R>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs371995616 CA9977777	245	R>P		No	ClinGen ESP ExAC TOPMed gnomAD
rs376901636 CA9977779	245	R>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA9977773 rs149843545	246	I>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs149843545 CA9977772	246	I>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA9977774 rs139751293	246	I>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	247	I>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	248	A>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977770 rs753721708	248	A>V		No	ClinGen ExAC gnomAD
CA409818451 rs760125718 CA9977768	249	M>I		No	ClinGen ExAC gnomAD
TCGA novel	249	M>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs763600502 CA9977769	249	M>V		No	ClinGen ExAC gnomAD
CA9977766 rs771816323	250	S>*		No	ClinGen ExAC gnomAD
rs771816323 CA9977767	250	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1164702145 CA409818461	251	F>S		No	ClinGen gnomAD
rs771485500 CA9977763	252	P>L		No	ClinGen ExAC gnomAD
rs771485500 CA409818468	252	P>R		No	ClinGen ExAC gnomAD
rs774840971 CA409818466	252	P>S		No	ClinGen ExAC TOPMed gnomAD
CA9977764 rs774840971	252	P>T		No	ClinGen ExAC TOPMed gnomAD
CA9977762 rs749740113	253	S>P		No	ClinGen ExAC gnomAD
CA9977761 rs778158530	253	S>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA9977760 rs769873939	254	S>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA409818480 rs1248684784	255	G>E	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA9977759 rs557388284 CA9977758	255	G>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1469146787 CA409818482	256	R>G		No	ClinGen gnomAD
rs751839881 CA9977756	256	R>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA9977753 rs753759047	257	Q>*		No	ClinGen ExAC TOPMed gnomAD
rs947389703 CA409818492	257	Q>H		No	ClinGen TOPMed
CA9977754 rs753759047	257	Q>K		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	257	Q>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977751 rs752229389	258	S>C		No	ClinGen ExAC gnomAD
rs752229389 CA9977750	258	S>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs763970376 CA9977752	258	S>T		No	ClinGen ExAC gnomAD
rs752229389 CA409818496	258	S>Y		No	ClinGen ExAC gnomAD
CA9977749 rs767190339	259	F>C		No	ClinGen ExAC gnomAD
rs568590987 CA9977748	259	F>L		No	ClinGen 1000Genomes ExAC gnomAD
rs767190339 CA409818501	259	F>S		No	ClinGen ExAC gnomAD
TCGA novel	259	F>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977747 rs368392876	260	Y>C		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	260	Y>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	261	R>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409818510 rs1323653855	261	R>G		No	ClinGen gnomAD
rs1473567685 CA409818512	261	R>K		No	ClinGen TOPMed
TCGA novel	261	R>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409818530 rs1402319455	263	P>L		No	ClinGen gnomAD
TCGA novel	263	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977746 rs763252474	264	I>F		No	ClinGen ExAC TOPMed gnomAD
rs1192032603 CA409818534	264	I>M		No	ClinGen TOPMed
rs555185771 CA317603721	264	I>N		No	ClinGen 1000Genomes
TCGA novel	264	I>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977745 rs763252474	264	I>V		No	ClinGen ExAC TOPMed gnomAD
TCGA novel rs534750768 CA9977741	265	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC TOPMed gnomAD NCI-TCGA
rs773734060 CA9977744	265	K>Q		No	ClinGen ExAC gnomAD
CA9977743 rs770173979	265	K>R		No	ClinGen ExAC gnomAD
TCGA novel	266	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1328516038 CA409818552	266	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1328516038 CA409818553	266	E>Q		No	ClinGen gnomAD
rs1314690861 CA409818562	267	V>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs778657533 CA409818561	267	V>F		No	ClinGen ExAC TOPMed gnomAD
rs778657533 CA9977688	267	V>I		No	ClinGen ExAC TOPMed gnomAD
rs1166228143 CA409818567	268	V>M		No	ClinGen gnomAD
CA9977686 rs754178012	269	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs141045272 CA9977687	269	R>W		No	ClinGen ESP ExAC TOPMed gnomAD
rs764500781 CA9977685	270	F>L		No	ClinGen ExAC gnomAD
rs764500781 CA409818575	270	F>V		No	ClinGen ExAC gnomAD
CA409818576 rs1480710700	270	F>Y		No	ClinGen gnomAD
CA9977683 rs74553878	272	D>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA9977684 rs761162465	272	D>H		No	ClinGen ExAC gnomAD
CA409818586 rs761162465	272	D>N		No	ClinGen ExAC gnomAD
CA9977681 rs534010574	273	K>*		No	ClinGen 1000Genomes ExAC gnomAD
CA9977682 rs534010574	273	K>E		No	ClinGen 1000Genomes ExAC gnomAD
CA409818594 rs1232536001	273	K>R		No	ClinGen gnomAD
rs1232536001 CA409818593	273	K>T		No	ClinGen gnomAD
CA409818605 rs1449928765	274	K>N		No	ClinGen TOPMed gnomAD
rs763319578 CA9977677	275	H>L		No	ClinGen ExAC gnomAD
CA409818609 rs776558201 CA9977675	275	H>Q		No	ClinGen ExAC gnomAD
rs763319578 CA9977676	275	H>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA317607379 rs571326171	275	H>Y		No	ClinGen 1000Genomes
rs148448130 CA9977673	276	R>*		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA9977674 rs148448130	276	R>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA9977672 rs200020621	276	R>L		No	ClinGen ExAC TOPMed gnomAD
CA9977671 rs200020621	276	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs1327006359 CA409818613	277	N>D		No	ClinGen gnomAD
CA409818611 rs1327006359	277	N>H		No	ClinGen gnomAD
rs1461301295 CA409818618	277	N>K		No	ClinGen TOPMed gnomAD
TCGA novel	278	H>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs778442291 CA9977670	278	H>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA9977668 rs749002591	278	H>P		No	ClinGen ExAC TOPMed gnomAD
CA9977667 rs749002591	278	H>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs778442291 CA9977669	278	H>Y		No	ClinGen ExAC gnomAD
rs1368844840 CA746906350	279	Y>*		No	ClinGen TOPMed
CA9977666 rs778041505	279	Y>C		No	ClinGen ExAC gnomAD
rs755481692 CA9977663	280	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs755481692 CA9977664	280	R>G		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	280	R>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs532485045 CA9977661	280	R>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs532485045 CA9977660	280	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA9977656 rs570106512	281	V>G		No	ClinGen 1000Genomes
rs773573743 CA9977658	281	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs773573743 CA9977659	281	V>L		No	ClinGen ExAC TOPMed gnomAD
rs760543605 CA9977654	282	Y>C		No	ClinGen ExAC gnomAD
rs760543605 CA409818637	282	Y>S		No	ClinGen ExAC gnomAD
rs745849745 CA9977651	283	N>D		No	ClinGen ExAC gnomAD
TCGA novel	283	N>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	283	N>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs550201639 CA9977650	283	N>S		No	ClinGen 1000Genomes ExAC gnomAD
rs745849745 CA9977652	283	N>Y		No	ClinGen ExAC gnomAD
rs1304526750 CA409818656	285	C>*		No	ClinGen gnomAD
CA9977647 rs777422330	285	C>R		No	ClinGen ExAC gnomAD
TCGA novel	285	C>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409818659 rs756392301	286	S>C		No	ClinGen ExAC TOPMed gnomAD
CA9977646 rs756392301	286	S>G		No	ClinGen ExAC TOPMed gnomAD
rs762873682 CA9977588	286	S>I		No	ClinGen ExAC TOPMed gnomAD
CA409818671 rs762873682	286	S>N		No	ClinGen ExAC TOPMed gnomAD
rs1430946858 CA409818676	287	E>Q		No	ClinGen TOPMed
CA9977587 rs149333450	288	R>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA9977586 rs764750519	288	R>T		No	ClinGen ExAC gnomAD
rs1555815970 CA9977584	289	A>D		No	ClinGen Ensembl
CA409818688 rs1360961339	289	A>T		No	ClinGen gnomAD
CA9977582 rs778991288	290	Y>*		No	ClinGen ExAC TOPMed
TCGA novel	290	Y>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977578 rs760460329	291	D>E		No	ClinGen ExAC gnomAD
rs373367615 CA9977580	291	D>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs373367615 CA9977579	291	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs373367615 CA317607803	291	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA409818705 rs1255325443	292	P>T		No	ClinGen TOPMed
TCGA novel	293	K>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs772565284 CA409818717	293	K>N		No	ClinGen ExAC TOPMed gnomAD
CA409818736 rs1235252872	296	H>D		No	ClinGen TOPMed
rs1241942614 CA409818740	296	H>L		No	ClinGen gnomAD
rs1235252872 CA409818735	296	H>Y		No	ClinGen TOPMed
CA409818743 rs1307200154	297	N>D		No	ClinGen gnomAD
TCGA novel	297	N>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs749295156 CA409818753	298	R>K		No	ClinGen ExAC gnomAD
CA9977572 rs749295156	298	R>M		No	ClinGen ExAC gnomAD
CA9977571 rs777956432	298	R>S		No	ClinGen ExAC TOPMed gnomAD
rs1555815998 CA9977568	299	V>A		No	ClinGen Ensembl
TCGA novel	299	V>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977570 rs139617622	299	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs139963428 CA9977564	300	V>F		No	ClinGen ESP ExAC TOPMed gnomAD
CA9977563 rs139963428	300	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA409818764 rs1471839718	301	R>G		No	ClinGen gnomAD
TCGA novel	301	R>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409818768 rs1464146574	301	R>K		No	ClinGen TOPMed
TCGA novel	302	I>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	302	I>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	302	I>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs753268180 CA9977561	302	I>N		No	ClinGen ExAC TOPMed gnomAD
CA409818773 rs753268180	302	I>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs757262160 CA9977562	302	I>V		No	ClinGen ExAC gnomAD
CA409818784 TCGA novel rs1236673150	303	M>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA ClinGen gnomAD
CA409818776 TCGA novel rs1439327538	303	M>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen gnomAD NCI-TCGA
CA9977559 rs200373866	304	I>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	304	I>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs763761168 CA9977560	304	I>T		No	ClinGen ExAC TOPMed gnomAD
rs1173912047 CA409818786	304	I>V		No	ClinGen TOPMed
TCGA novel	305	D>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs775291247 CA9977558	305	D>Y		No	ClinGen ExAC gnomAD
CA409818800 rs1301828196	306	D>E		No	ClinGen gnomAD
rs759848069 CA317607865	306	D>G		No	ClinGen ExAC TOPMed gnomAD
rs759848069 CA9977556	306	D>V		No	ClinGen ExAC TOPMed gnomAD
CA9977557 rs767943361	306	D>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
TCGA novel	307	H>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977555 rs774817598	307	H>R		No	ClinGen ExAC gnomAD
CA409818810 rs1238898616	308	N>D		No	ClinGen gnomAD
TCGA novel	308	N>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977554 rs771318641	308	N>S		No	ClinGen ExAC gnomAD
TCGA novel	309	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977550 rs748311592	309	V>D		No	ClinGen ExAC gnomAD
rs373623566 CA9977552	309	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
CA9977551 rs373623566	309	V>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA9977546 rs142719163	310	P>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA9977545 rs142719163	310	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs745622481 CA9977547	310	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs745622481 CA9977548	310	P>T		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	311	T>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs199963822 CA9977540	312	L>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA9977541 rs199963822	312	L>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA9977537 rs564242982	313	H>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs564242982 CA9977536	313	H>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs377711707 CA9977538	313	H>Y		No	ClinGen ESP ExAC TOPMed gnomAD
rs4094946 CA9977473	314	Q>*		No	ClinGen ExAC TOPMed gnomAD
rs4094946 CA9977472	314	Q>E		No	ClinGen ExAC TOPMed gnomAD
rs375679452 CA9977470	314	Q>H		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	314	Q>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs571590085 CA9977471	314	Q>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs571590085 CA409818848	314	Q>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs754298589 CA9977467	315	M>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA409818853 rs757639152	315	M>K		No	ClinGen ExAC gnomAD
rs779188578 CA9977469	315	M>L		No	ClinGen ExAC TOPMed gnomAD
CA9977468 rs757639152	315	M>T		No	ClinGen ExAC gnomAD
rs779188578 CA409818851	315	M>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA409818857 rs764628536	316	V>L		No	ClinGen ExAC TOPMed gnomAD
CA9977466 rs764628536	316	V>M		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	317	V>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	318	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977464 rs558058436	319	T>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs538136276 CA9977463	319	T>I		No	ClinGen 1000Genomes ExAC gnomAD
CA409818879 rs538136276	319	T>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA gnomAD
TCGA novel	320	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs774728792 CA9977461	320	K>R		No	ClinGen ExAC TOPMed gnomAD
rs774728792 CA409818883	320	K>T		No	ClinGen ExAC TOPMed gnomAD
CA409818889 rs1463937346	321	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
TCGA novel	321	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977459 rs761732225	322	V>L		No	ClinGen ExAC TOPMed gnomAD
rs746981324 CA9977456	323	N>D		No	ClinGen ExAC gnomAD
TCGA novel rs1600943006 CA409818904	323	N>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
CA9977455 rs775063074	323	N>S		No	ClinGen ExAC gnomAD
CA9977454 rs771577928	324	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1600943032 CA409818909	324	E>V		No	ClinGen Ensembl
rs1405114738 CA409818915	325	W>*		No	ClinGen gnomAD
CA9977451 rs756940047	325	W>C		No	ClinGen ExAC gnomAD
rs145674850 CA9977452	325	W>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs1308850547 CA409818922	326	M>K		No	ClinGen gnomAD
CA409818923 rs1308850547	326	M>T		No	ClinGen gnomAD
CA9977450 rs749639367	326	M>V		No	ClinGen ExAC gnomAD
rs756637390 CA9977448	327	A>G		No	ClinGen ExAC TOPMed gnomAD
rs778056355 CA9977449	327	A>P		No	ClinGen ExAC gnomAD
CA9977445 rs767577291	328	Q>E		No	ClinGen ExAC gnomAD
CA9977440 rs569151332	329	D>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs763319592 CA9977442	329	D>G		No	ClinGen ExAC gnomAD
TCGA novel	329	D>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977443 rs751792307	329	D>N		No	ClinGen ExAC gnomAD
rs763319592 CA9977441	329	D>V		No	ClinGen ExAC gnomAD
CA9977444 rs751792307	329	D>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA409818942 rs1419823055	330	L>F		No	ClinGen gnomAD
TCGA novel	330	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977438 rs760596997	330	L>P		No	ClinGen ExAC gnomAD
rs1455374739 CA409818951	331	E>G		No	ClinGen gnomAD
rs1259242864 CA409818957	332	N>H		No	ClinGen Ensembl
CA409818965 rs1190511832	333	I>N		No	ClinGen gnomAD
rs775309084 CA9977437	333	I>V		No	ClinGen ExAC gnomAD
CA9977432 rs149228869	334	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA9977434 rs149228869 CA9977433	334	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA9977430 rs371882723	335	A>E		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	335	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977429 rs371882723	335	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA409818977 rs751667955	336	I>F		No	ClinGen ExAC TOPMed gnomAD
rs780342614 CA9977425	336	I>T		No	ClinGen ExAC gnomAD
CA9977426 rs751667955	336	I>V		No	ClinGen ExAC TOPMed gnomAD
rs1302442512 CA409818981	337	H>N	Variant assessed as Somatic; 4.619e-05 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1302442512 CA409818983	337	H>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs750618460 CA409818993	338	C>F		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	338	C>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs750618460 CA9977423	338	C>Y		No	ClinGen ExAC TOPMed gnomAD
CA9977422 rs763895749	339	K>E		No	ClinGen ExAC gnomAD
rs1379105045 CA409819000	339	K>I		No	ClinGen TOPMed
TCGA novel	339	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	340	G>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1206013199 CA409819011	341	G>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs760415994 CA9977421	341	G>S		No	ClinGen ExAC gnomAD
TCGA novel	341	G>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	342	T>=	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs767416660 CA9977419	342	T>A		No	ClinGen ExAC gnomAD
rs759523599 CA409819017	342	T>I		No	ClinGen ExAC TOPMed gnomAD
CA9977418 rs759523599	342	T>R		No	ClinGen ExAC TOPMed gnomAD
rs767416660 CA409819015	342	T>S		No	ClinGen ExAC gnomAD
rs763812669 CA9977351	343	D>G		No	ClinGen ExAC TOPMed gnomAD
rs770431415 CA9977416	343	D>N		No	ClinGen ExAC gnomAD
TCGA novel	343	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409819039 rs1162716274	344	R>G		No	ClinGen TOPMed gnomAD
TCGA novel	344	R>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409819042 rs1456490474	344	R>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs760458375 CA9977350	345	T>I		No	ClinGen ExAC gnomAD
rs752996568 CA9977349	346	G>E	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
TCGA novel	346	G>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs767925419 CA9977348	347	T>A		No	ClinGen ExAC gnomAD
CA9977347 rs759901111	347	T>N		No	ClinGen ExAC gnomAD
CA409819066 rs770958415 CA9977345	348	M>I		No	ClinGen ExAC TOPMed gnomAD
CA409819062 rs1353219798	348	M>K		No	ClinGen TOPMed
rs774942411 CA9977346	348	M>V		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	349	V>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs762988096 CA317613440	349	V>I		No	ClinGen ExAC gnomAD
rs762988096 CA9977344	349	V>L		No	ClinGen ExAC gnomAD
CA317613445 rs202169239	350	C>F		No	ClinGen 1000Genomes gnomAD
TCGA novel	351	A>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs773329925 CA9977343	351	A>T		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	351	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977341 rs148651545	352	F>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs779650133 CA9977340	353	L>V		No	ClinGen ExAC gnomAD
rs374102942 CA9977338	354	I>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs777490013 CA9977334	355	A>G		No	ClinGen ExAC TOPMed gnomAD
rs757306400 CA9977337	355	A>S		No	ClinGen ExAC TOPMed gnomAD
CA9977336 rs757306400	355	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs777490013 CA9977335	355	A>V		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	356	S>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1162654957 CA409819108	356	S>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
TCGA novel	356	S>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	356	S>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977331 rs575650462	357	E>K		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA9977329 rs370631185	358	I>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs1174648889 CA409819121	358	I>M		No	ClinGen gnomAD
rs370631185 CA409819119	358	I>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs367973111 CA9977327	359	C>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs367973111 CA409819123	359	C>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1377549344 CA409819124	359	C>Y		No	ClinGen gnomAD
CA9977325 rs763509744	361	T>A	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs773278292 CA9977324	361	T>S		No	ClinGen ExAC gnomAD
rs144150406 CA9977323	362	A>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs761887091 CA9977322	362	A>V		No	ClinGen ExAC gnomAD
rs1200817152 CA409819144	363	K>E		No	ClinGen gnomAD
CA9977320 rs73336307 CA9977319	363	K>N		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	364	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977260 rs752863082	365	S>N		No	ClinGen ExAC gnomAD
rs557556075 CA9977259	365	S>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA409819170 rs752863082	365	S>T		No	ClinGen ExAC gnomAD
CA9977258 rs759896199	366	L>P		No	ClinGen ExAC gnomAD
rs1425262032 CA409819181	367	Y>C		No	ClinGen TOPMed
rs750239904 CA409819189	368	Y>C		No	ClinGen ExAC gnomAD
rs750239904 CA9977257	368	Y>F		No	ClinGen ExAC gnomAD
TCGA novel	369	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	369	F>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs764947521 CA9977256	369	F>Y		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	371	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409819212 rs1448997269	371	E>D		No	ClinGen TOPMed
TCGA novel	371	E>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1568768090 CA409819206	371	E>Q		No	ClinGen Ensembl
rs1242592108 CA409819213	372	R>G		No	ClinGen TOPMed gnomAD
TCGA novel	372	R>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977254 rs537312499	373	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA9977253 rs568780841	373	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	374	T>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs775033829 CA9977251	374	T>I		No	ClinGen ExAC gnomAD
TCGA novel	375	D>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1600971676 CA409819234	375	D>E		No	ClinGen Ensembl
TCGA novel	375	D>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409819229 rs1435060214	375	D>N		No	ClinGen gnomAD
CA409819232 rs1389865708	375	D>V		No	ClinGen TOPMed gnomAD
CA409819238 rs1363177690	376	K>*		No	ClinGen gnomAD
rs1363177690 CA409819237	376	K>E		No	ClinGen gnomAD
TCGA novel	376	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1419954462 CA409819248	377	T>I		No	ClinGen gnomAD
CA9977249 rs368593383	377	T>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	378	H>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977248 rs779276041	378	H>N		No	ClinGen ExAC gnomAD
CA9977247 rs771218867	378	H>R		No	ClinGen ExAC gnomAD
TCGA novel	379	S>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	379	S>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977245 rs778109490	379	S>R		No	ClinGen ExAC gnomAD
CA9977243 CA409819260 rs371388267	379	S>R		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	379	S>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977241 rs755184182	380	E>D		No	ClinGen ExAC gnomAD
CA9977242 rs781489069	380	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1219005434 CA409819268	381	K>E		No	ClinGen gnomAD
TCGA novel	381	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs751845563 CA9977240	381	K>R		No	ClinGen ExAC gnomAD
TCGA novel	382	F>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	382	F>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	383	Q>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	383	Q>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs142165446 CA9977238	384	G>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
rs142165446 TCGA novel CA9977239	384	G>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD NCI-TCGA
rs1314325002 CA409819293	384	G>V		No	ClinGen gnomAD
CA9977236 rs763919484	385	V>I		No	ClinGen ExAC TOPMed gnomAD
CA317614204 rs212146	386	K>*		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs212146 VAR_065097 CA9977235	386	K>E		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs212146 CA317614194	386	K>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs774909292 CA9977234	386	K>R		No	ClinGen ExAC gnomAD
CA409819304 rs1359494616	387	T>A		No	ClinGen gnomAD
rs767024313 CA9977233	387	T>I		No	ClinGen ExAC gnomAD
TCGA novel	388	P>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs773903588 CA9977231	388	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA409819308 rs759137049	388	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA9977232 rs759137049	388	P>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1427778942	389	S>missing	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1175222524 CA409819317	389	S>F		No	ClinGen gnomAD
rs773683205 CA9977228	390	Q>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
TCGA novel	390	Q>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977229 rs749592520	390	Q>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs754185411	391	K>=	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
CA9977168 rs754185411	391	K>N		No	ClinGen ExAC gnomAD
rs764581952 CA9977166	392	R>*		No	ClinGen ExAC gnomAD
TCGA novel	392	R>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409819341 rs1201661482	392	R>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
TCGA novel	393	Y>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs761585045	393	Y>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977164 rs146018947	393	Y>C		No	ClinGen ESP ExAC TOPMed gnomAD
CA409819347 rs761069467	393	Y>D		No	ClinGen ExAC TOPMed gnomAD
CA9977165 rs761069467	393	Y>H		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	394	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1286371238 CA409819356	394	V>G		No	ClinGen gnomAD
rs1348096962 CA409819352	394	V>I		No	ClinGen TOPMed
rs1348096962 CA9977161	394	V>L		No	ClinGen TOPMed
rs759614386 CA9977160	395	A>G		No	ClinGen ExAC TOPMed gnomAD
rs1204319921 CA409819357	395	A>T		No	ClinGen gnomAD
rs1346175489 CA409819367 CA409819368	396	Y>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen gnomAD NCI-TCGA
rs771076869 CA9977158	396	Y>C		No	ClinGen ExAC TOPMed gnomAD
CA409819372 rs1300915060	397	F>S		No	ClinGen TOPMed
CA9977157 rs749579434	397	F>V		No	ClinGen ExAC gnomAD
rs555626581 CA409819376	398	A>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs555626581 CA9977156	398	A>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA409819380 rs1342604003	398	A>V		No	ClinGen gnomAD
rs573185698 CA9977153	399	Q>*		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA9977152 rs758288447	399	Q>H		No	ClinGen ExAC gnomAD
rs573185698 CA9977154	399	Q>K		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA9977150 rs778568094	400	V>A		No	ClinGen ExAC gnomAD
CA9977151 rs749892686 CA409819387	400	V>L		No	ClinGen ExAC gnomAD
rs146717676 CA9977148	401	K>E		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	402	H>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409819402 rs1445024812	402	H>Q		No	ClinGen gnomAD
rs756465436 CA9977146	402	H>R		No	ClinGen ExAC gnomAD
rs1263386872 CA409819399	402	H>Y		No	ClinGen TOPMed gnomAD
CA9977145 rs753029047	403	L>F		No	ClinGen ExAC
TCGA novel	403	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs139488785 CA9977142	404	Y>S		No	ClinGen ESP TOPMed gnomAD
CA409819418 rs1568778378	405	N>D		No	ClinGen Ensembl
TCGA novel	405	N>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409819426 rs1221748195	406	W>*		No	ClinGen TOPMed gnomAD
CA409819430 rs1342464348	406	W>*		No	ClinGen TOPMed gnomAD
CA409819429 rs1342464348	406	W>C		No	ClinGen TOPMed gnomAD
CA9977139 rs774411073	406	W>R		No	ClinGen ExAC gnomAD
rs1163669069 CA409819437	407	N>S		No	ClinGen gnomAD
rs267606169 CA317615445	408	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
TCGA novel	408	L>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel CA409819440 rs267606169	408	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA Ensembl
rs1430308618 CA409819447	409	P>A		No	ClinGen TOPMed gnomAD
rs763139804 CA9977137	409	P>L		No	ClinGen ExAC gnomAD
rs1430308618 CA409819446	409	P>S		No	ClinGen TOPMed gnomAD
rs769940388 CA9977135	410	P>A		No	ClinGen ExAC TOPMed gnomAD
CA9977134 rs775159573	410	P>L		No	ClinGen ExAC TOPMed gnomAD
CA9977133 rs775159573	410	P>R		No	ClinGen ExAC TOPMed gnomAD
CA409819450 rs769940388	410	P>S		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	411	R>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	411	R>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs756871735 CA9977130	412	R>L		No	ClinGen ExAC TOPMed gnomAD
CA9977129 rs756871735	412	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA9977131 rs143510517	412	R>W		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	413	I>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs777436958 CA9977128	413	I>M		No	ClinGen ExAC gnomAD
CA9977125 rs753041627	414	L>F		No	ClinGen ExAC TOPMed gnomAD
rs767837848 CA9977124	414	L>H		No	ClinGen ExAC gnomAD
rs767837848 CA409819469	414	L>P		No	ClinGen ExAC gnomAD
CA9977126 rs753041627	414	L>V		No	ClinGen ExAC TOPMed gnomAD
rs1187994641 CA409819484	416	I>M		No	ClinGen gnomAD
rs755465026 CA9977123	416	I>V		No	ClinGen ExAC gnomAD
CA9977122 rs752110213	417	K>R		No	ClinGen ExAC gnomAD
CA409819494 rs1432864309	418	H>N		No	ClinGen TOPMed
rs766414837 CA9977119	418	H>P		No	ClinGen ExAC TOPMed gnomAD
CA409819497 rs1159029352	418	H>Q		No	ClinGen TOPMed
rs766414837 CA409819495	418	H>R		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	418	H>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977118 rs762979710	419	F>I		No	ClinGen ExAC gnomAD
rs539061665 CA9977117	419	F>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA409819505 rs1214103584	420	I>L		No	ClinGen gnomAD
CA409819508 rs761942601	420	I>N		No	ClinGen ExAC gnomAD
CA9977115 rs761942601	420	I>S		No	ClinGen ExAC gnomAD
CA409819509 rs761942601	420	I>T		No	ClinGen ExAC gnomAD
rs1214103584 CA409819506	420	I>V		No	ClinGen gnomAD
TCGA novel	421	I>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1286237741 CA409819513	421	I>V		No	ClinGen gnomAD
CA409819523 rs1162958799	422	Y>*		No	ClinGen TOPMed
rs772047311 CA9977113	422	Y>F		No	ClinGen ExAC TOPMed gnomAD
CA9977114 rs775347600	422	Y>H		No	ClinGen ExAC gnomAD
rs570468666 CA9977112	423	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs771019119 CA9977110	424	I>T		No	ClinGen ExAC TOPMed gnomAD
CA9977107 rs747814822	425	P>L		No	ClinGen ExAC TOPMed gnomAD
CA9977106 rs747814822	425	P>R		No	ClinGen ExAC TOPMed gnomAD
rs138794341 CA9977108	425	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	425	P>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977104 rs150256961	426	R>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs150256961 CA9977105	426	R>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA9977050 rs374643597	426	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA317616349 rs374643597	426	R>L		No	ClinGen ExAC gnomAD
CA9977048 rs141919406	427	Y>*		No	ClinGen ESP ExAC TOPMed gnomAD
CA409819552 rs1469295222	427	Y>C		No	ClinGen TOPMed gnomAD
rs1175629199 CA409819549	427	Y>D		No	ClinGen TOPMed gnomAD
CA409819550 rs1175629199	427	Y>H		No	ClinGen TOPMed gnomAD
CA9977046 rs771783444	429	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs746164402 CA9977045	429	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA409819570 rs1244217159	430	D>E		No	ClinGen TOPMed gnomAD
rs1185130243 CA409819565	430	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA9977044 rs774787076	430	D>V		No	ClinGen ExAC gnomAD
CA409819575 rs1469906857	431	L>P		No	ClinGen TOPMed
CA409819572 rs1007047312	431	L>V		No	ClinGen TOPMed gnomAD
rs1461137118 CA409819583	432	K>N		No	ClinGen gnomAD
rs1253677511 CA409819585	433	I>L		No	ClinGen TOPMed
CA9977042 rs771341118	434	Q>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
TCGA novel rs1252534610 CA409819597	434	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA ClinGen gnomAD
CA409819596 rs1459555969	434	Q>L		No	ClinGen TOPMed gnomAD
rs1459555969 CA409819594	434	Q>P		No	ClinGen TOPMed gnomAD
CA9977041 rs749871986	435	I>M		No	ClinGen ExAC gnomAD
CA409819604 rs1227567112	435	I>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
TCGA novel	436	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs748269755 CA9977038	436	E>D		No	ClinGen ExAC gnomAD
CA9977039 rs553246393	436	E>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	436	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs777978866 CA9977040	436	E>Q		No	ClinGen ExAC TOPMed gnomAD
CA9977036 rs755241504 CA409819615	437	M>I		No	ClinGen ExAC TOPMed gnomAD
CA9977037 rs781224316	437	M>T		No	ClinGen ExAC TOPMed gnomAD
CA409819624 rs1402432377	438	E>D	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1443714288 CA409819621	438	E>G		No	ClinGen TOPMed
rs1299965815 CA409819627	439	K>*		No	ClinGen TOPMed gnomAD
rs1299965815 CA409819626	439	K>E	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA9977035 rs750118466	439	K>R		No	ClinGen ExAC gnomAD
CA9977032 rs757127690	441	V>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA9977033 rs757127690	441	V>I		No	ClinGen ExAC gnomAD
TCGA novel	442	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	442	V>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409819654 rs1183421286	443	F>S		No	ClinGen gnomAD
CA409819661 rs760134432	444	S>C		No	ClinGen ExAC TOPMed gnomAD
CA9977028 rs760134432	444	S>F		No	ClinGen ExAC TOPMed gnomAD
CA9977029 rs763560950	444	S>P		No	ClinGen ExAC TOPMed gnomAD
rs1168082171	444	S>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977026 rs767015423	445	T>I		No	ClinGen ExAC TOPMed gnomAD
CA409819664 rs767015423	445	T>N		No	ClinGen ExAC TOPMed gnomAD
CA409819662 rs774999244	445	T>P		No	ClinGen ExAC
rs767015423 CA409819665	445	T>S		No	ClinGen ExAC TOPMed gnomAD
CA9977027 rs774999244	445	T>S		No	ClinGen ExAC
rs1249187064 CA409819668	446	I>F		No	ClinGen TOPMed gnomAD
rs1249187064 CA409819667	446	I>V		No	ClinGen TOPMed gnomAD
TCGA novel	447	S>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9977025 rs759301774	447	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
TCGA novel	447	S>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1314078554 CA409819681	448	L>*		No	ClinGen gnomAD
rs893673415 CA317616449	448	L>V		No	ClinGen TOPMed
CA9977022 rs749783984	449	G>E	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1483152250 CA409819684	449	G>R		No	ClinGen TOPMed
rs749783984 CA409819688	449	G>V		No	ClinGen ExAC TOPMed gnomAD
CA409819696 rs1391972379	450	K>N		No	ClinGen gnomAD
CA9977020 rs770447075	451	C>Y		No	ClinGen ExAC TOPMed gnomAD
CA409819707 rs147105244	452	S>*		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs768753774	452	S>=	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
CA9977018 rs147105244	452	S>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA9977019 rs147105244	452	S>W		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs750148266 CA9976965	453	V>I		No	ClinGen ExAC TOPMed gnomAD
rs750148266 CA9976966	453	V>L		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	454	L>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	454	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9976964 rs765665858	454	L>V		No	ClinGen ExAC gnomAD
TCGA novel	455	D>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	455	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9976963 rs757597999	455	D>V		No	ClinGen ExAC gnomAD
TCGA novel	456	N>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409819739 rs1339213944	456	N>S		No	ClinGen gnomAD
rs1168871321 CA409819746	457	I>T		No	ClinGen gnomAD
CA9976962 rs754172584	457	I>V		No	ClinGen ExAC TOPMed gnomAD
rs1398670772 CA409819751	458	T>A		No	ClinGen TOPMed
CA409819752 rs761088080	458	T>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA9976960 rs761088080	458	T>K		No	ClinGen ExAC gnomAD
CA9976959 rs761088080	458	T>R		No	ClinGen ExAC gnomAD
CA9976958 rs775537174	459	T>A		No	ClinGen ExAC TOPMed gnomAD
rs759727745 CA9976956	459	T>I		No	ClinGen ExAC TOPMed gnomAD
CA9976957 rs759727745	459	T>K		No	ClinGen ExAC TOPMed gnomAD
rs1393711343 CA409819758	460	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs774516826 CA9976955	461	K>E		No	ClinGen ExAC gnomAD
TCGA novel	461	K>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409819775 rs1455136362	462	I>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA9976953 rs747920313	462	I>T		No	ClinGen ExAC gnomAD
CA9976954 rs771164931	462	I>V		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	462	I>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	463	L>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs776296746 CA9976952	463	L>S		No	ClinGen ExAC gnomAD
rs1363734169 CA409819777	463	L>V		No	ClinGen TOPMed
TCGA novel	464	I>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs768632607 CA9976951	464	I>V		No	ClinGen ExAC gnomAD
rs745399187 CA9976947	465	D>E		No	ClinGen ExAC gnomAD
CA9976948 rs375070018	465	D>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA9976950 rs746975259	465	D>N		No	ClinGen ExAC TOPMed
rs375070018 CA9976949	465	D>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA409819794 rs1250449526	466	V>E		No	ClinGen gnomAD
CA9976946 rs778656033	466	V>I		No	ClinGen ExAC TOPMed gnomAD
CA9976942 rs375879420 CA9976941	467	F>L		No	ClinGen ExAC TOPMed gnomAD
rs764426950 CA9976943	467	F>Y		No	ClinGen ExAC TOPMed gnomAD
CA409819802 rs774428997	468	D>H		No	ClinGen ExAC TOPMed gnomAD
CA9976938 rs774428997	468	D>N		No	ClinGen ExAC TOPMed gnomAD
CA9976939 rs774428997	468	D>Y		No	ClinGen ExAC TOPMed gnomAD
CA9976936 rs763153044	469	G>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	469	G>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409819808 rs763153044	469	G>S		No	ClinGen ExAC TOPMed gnomAD
rs1354640466 CA409819813	470	L>I		No	ClinGen TOPMed gnomAD
VAR_025400 rs150482 CA9976935	470	L>P		No	ClinGen UniProt 1000Genomes ExAC TOPMed dbSNP gnomAD
CA409819816 rs150482	470	L>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA409819814 rs1354640466	470	L>V		No	ClinGen TOPMed gnomAD
CA9976933 rs760629727	471	P>L		No	ClinGen ExAC gnomAD
CA409819817 rs1600993043	471	P>S		No	ClinGen Ensembl
TCGA novel	472	L>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1414458154 CA409819823	472	L>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA9976928 CA409819832 rs778568331	473	Y>*		No	ClinGen ExAC gnomAD
CA9976929 rs745316124	473	Y>C		No	ClinGen ExAC gnomAD
TCGA novel	474	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel rs748945618 CA9976926	475	D>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC gnomAD NCI-TCGA
rs1314927846 CA409819841	475	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs770609988 CA9976927	475	D>V		No	ClinGen ExAC gnomAD
TCGA novel	476	V>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1482196458 CA409819847	476	V>M		No	ClinGen gnomAD
rs1223616174 CA409819854	477	K>E		No	ClinGen gnomAD
rs756398586 CA9976924	478	V>M		No	ClinGen ExAC TOPMed gnomAD
rs755481564 CA409819867	479	Q>*		No	ClinGen ExAC TOPMed gnomAD
rs755481564 CA9976921	479	Q>K		No	ClinGen ExAC TOPMed gnomAD
CA9976920 rs751635609	479	Q>R		No	ClinGen ExAC TOPMed gnomAD
rs766425558 CA9976919	480	F>V		No	ClinGen ExAC gnomAD
rs750650542 CA9976916	481	F>L		No	ClinGen ExAC TOPMed
CA9976918 rs763210612	481	F>L		No	ClinGen ExAC gnomAD
rs1346991719 CA409819882	481	F>S		No	ClinGen TOPMed gnomAD
rs9996 CA9976914	482	Y>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA9976915 rs765526982	482	Y>H		No	ClinGen ExAC TOPMed gnomAD
rs9996 CA9976913 VAR_061895	482	Y>S		No	ClinGen UniProt 1000Genomes ExAC TOPMed dbSNP gnomAD
CA9976911 rs773893493	483	S>*		No	ClinGen ExAC TOPMed gnomAD
CA9976910 rs773893493	483	S>L		No	ClinGen ExAC TOPMed gnomAD
CA409819891 rs1347924791	483	S>P		No	ClinGen gnomAD
CA409819890 rs1347924791	483	S>T		No	ClinGen gnomAD
CA409819908 rs1408933974	484	N>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs779199298 CA9976761	485	L>F		No	ClinGen ExAC
TCGA novel	485	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1448069894 CA409819920	486	P>L		No	ClinGen gnomAD
CA9976760 rs757759527	486	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs532224827 CA9976758	487	T>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1430694330 CA409819924	487	T>I		No	ClinGen gnomAD
CA9976752 rs769521893	488	Y>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs148862984 CA9976753	488	Y>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs146928839 CA9976755	488	Y>D		No	ClinGen ESP ExAC TOPMed gnomAD
rs146928839 CA9976754	488	Y>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA409819936 rs200633993	489	Y>*		No	ClinGen 1000Genomes ExAC gnomAD
rs549704276 CA9976751	489	Y>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA409819943 rs1236955411	490	D>E		No	ClinGen gnomAD
rs1473140271 CA409819937	490	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA9976749 rs768731357	491	N>H		No	ClinGen ExAC gnomAD
TCGA novel	491	N>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9976748 rs529676177	491	N>S		No	ClinGen 1000Genomes ExAC gnomAD
rs771832897 CA9976747	492	C>F		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	492	C>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409819956 rs1431634382	492	C>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA9976746 rs771832897	492	C>Y		No	ClinGen ExAC TOPMed gnomAD
CA9976744 rs757521579	493	S>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs757521579 CA9976743	493	S>L		No	ClinGen ExAC TOPMed gnomAD
rs745555372 CA9976745	493	S>P		No	ClinGen ExAC gnomAD
rs778188505 CA9976741	495	Y>*		No	ClinGen ExAC gnomAD
rs1356305685 CA409819969	495	Y>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA409819981 TCGA novel rs1482904884 CA409819982	496	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA ClinGen TOPMed
rs1443822256 CA409819977	496	F>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1231704238 CA409819988	497	W>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
TCGA novel	497	W>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs767633388 CA9976738	499	H>P		No	ClinGen ExAC gnomAD
CA317618717 rs796722833	499	H>Q		No	ClinGen TOPMed
rs752760516 CA9976739	499	H>Y		No	ClinGen ExAC gnomAD
CA409820005 rs1367238972	500	T>A		No	ClinGen TOPMed gnomAD
TCGA novel rs1600996595 CA409820009	500	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA Ensembl
CA409820010 rs761460005	501	S>A		No	ClinGen ExAC gnomAD
CA409820013 rs1411624452	501	S>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA9976734 rs761460005	501	S>P		No	ClinGen ExAC gnomAD
CA9976735 rs761460005	501	S>T		No	ClinGen ExAC gnomAD
TCGA novel	501	S>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	502	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs776570136 CA9976732	503	I>F		No	ClinGen ExAC TOPMed
CA9976731 rs527406045	503	I>T		No	ClinGen 1000Genomes ExAC gnomAD
CA409820030 rs1288697280	504	E>G		No	ClinGen gnomAD
rs775113189 CA9976729	504	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA9976728 rs771748827	505	N>S		No	ClinGen ExAC TOPMed gnomAD
rs879146658 CA317618774	506	N>D		No	ClinGen Ensembl
CA9976726 rs773825579	506	N>K		No	ClinGen ExAC
rs745413372 CA9976727	506	N>S		No	ClinGen ExAC gnomAD
CA317618785 rs201582298	507	R>K		No	ClinGen 1000Genomes gnomAD
rs779962709 CA9976677	507	R>S		No	ClinGen ExAC TOPMed gnomAD
CA409820047 rs1451520909	507	R>W		No	ClinGen TOPMed gnomAD
CA409820061 rs1432945554	508	L>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
TCGA novel	508	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs772237648 CA9976675	509	Y>C		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	509	Y>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs779218112 CA9976673	510	L>P		No	ClinGen ExAC TOPMed gnomAD
CA409820079 rs1419182732	511	P>S		No	ClinGen gnomAD
CA409820085 rs1170862146	512	K>*		No	ClinGen gnomAD
TCGA novel	512	K>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	512	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	512	K>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9976671 rs752528007	512	K>R		No	ClinGen ExAC gnomAD
TCGA novel	513	N>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	513	N>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	513	N>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9976669 rs754840934	513	N>S		No	ClinGen ExAC TOPMed gnomAD
rs754840934 CA9976670	513	N>T		No	ClinGen ExAC TOPMed gnomAD
CA409820097 TCGA novel rs751475912	514	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA ExAC gnomAD
CA409820098 rs766253736	514	E>A		No	ClinGen ExAC TOPMed gnomAD
CA409820100 rs372871658	514	E>D		No	ClinGen ESP ExAC TOPMed gnomAD
CA9976667 rs766253736	514	E>G		No	ClinGen ExAC TOPMed gnomAD
rs751475912 CA9976668	514	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA409820099 rs766253736	514	E>V		No	ClinGen ExAC TOPMed gnomAD
rs761508227 CA9976663	516	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
TCGA novel	516	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409820124 rs776836004	518	L>I		No	ClinGen ExAC gnomAD
CA9976662 rs776836004	518	L>V		No	ClinGen ExAC gnomAD
CA9976659 rs776015776	519	H>R		No	ClinGen ExAC TOPMed gnomAD
rs760975106 CA9976660	519	H>Y		No	ClinGen ExAC
TCGA novel	520	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs745874858 CA409820145	521	Q>L		No	ClinGen ExAC gnomAD
rs745874858 CA9976658	521	Q>P		No	ClinGen ExAC gnomAD
CA9976657 rs745874858	521	Q>R		No	ClinGen ExAC gnomAD
rs1262072150 CA409820151	522	K>I		No	ClinGen TOPMed
TCGA novel	522	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs779199857 CA409820157	523	A>P		No	ClinGen ExAC
rs779199857 CA9976656	523	A>S		No	ClinGen ExAC
rs537829038 CA409820161	524	R>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs749565759 CA409820162	524	R>P		No	ClinGen ExAC TOPMed gnomAD
CA9976653 rs749565759	524	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs537829038 CA9976654	524	R>W		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs376317057 CA9976650	525	R>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	525	R>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	525	R>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs535557577 CA9976649	526	I>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA9976648 rs758400092	526	I>N		No	ClinGen ExAC gnomAD
CA409820172 rs758400092	526	I>T		No	ClinGen ExAC gnomAD
CA9976646 rs764772581	527	Y>C		No	ClinGen ExAC TOPMed
CA9976647 rs567724468	527	Y>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	528	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	528	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	529	S>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1369604042 CA409820187	529	S>T		No	ClinGen gnomAD
TCGA novel	530	D>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409820197 rs1421544267	530	D>G		No	ClinGen gnomAD
rs761421704 CA9976645	530	D>H		No	ClinGen ExAC gnomAD
TCGA novel	531	F>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409820202 rs1182485036	531	F>V		No	ClinGen gnomAD
rs868380365 CA317620481	532	A>V		No	ClinGen TOPMed
TCGA novel	533	V>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1211489256 CA409820217	533	V>G		No	ClinGen TOPMed gnomAD
CA409820214 rs373095461	533	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA9976643 rs373095461	533	V>M		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	534	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1319960887 TCGA novel CA409820225	534	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA409820227 rs761042461	535	I>L		No	ClinGen ExAC TOPMed gnomAD
CA9976642 rs761042461	535	I>V		No	ClinGen ExAC TOPMed gnomAD
rs775720107 CA9976641	536	L>F		No	ClinGen ExAC gnomAD
rs768133066 CA9976640	536	L>R		No	ClinGen ExAC gnomAD
TCGA novel	537	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs774542896 CA9976638	537	F>L		No	ClinGen ExAC gnomAD
rs1229208656 CA409820248	538	G>D		No	ClinGen gnomAD
TCGA novel	538	G>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	538	G>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9976635 rs369994889	539	E>*		No	ClinGen ESP ExAC TOPMed gnomAD
rs1388898170 CA409820251	539	E>G		No	ClinGen gnomAD
CA9976634 rs369994889	539	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA409820255 rs746818662	540	K>E		No	ClinGen ExAC gnomAD
CA9976633 rs746818662	540	K>Q		No	ClinGen ExAC gnomAD
TCGA novel	540	K>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs758305832 CA9976631 CA317620513	541	M>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
TCGA novel	541	M>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA409820266 rs779885514	541	M>R		No	ClinGen ExAC gnomAD
CA9976632 rs779885514	541	M>T		No	ClinGen ExAC gnomAD
CA409820270 rs1173421612	542	T>A		No	ClinGen gnomAD
CA9976630 rs146524466	542	T>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs146524466 CA409820271	542	T>N		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	542	T>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA9976629 rs527927451	543	S>F		No	ClinGen 1000Genomes ExAC gnomAD
CA9976627 rs571598993	544	S>G	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes NCI-TCGA TOPMed
CA409820281 rs1409385803	544	S>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA9976626 rs756738534	544	S>R		No	ClinGen ExAC TOPMed gnomAD
rs759410796	544	S>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
rs755786653 CA9976623	545	D>G		No	ClinGen ExAC TOPMed gnomAD
rs267606168 CA9976624	545	D>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA317620541 rs267606168	545	D>N		No	ClinGen ESP ExAC TOPMed gnomAD
CA409820285 rs755786653	545	D>V		No	ClinGen ExAC TOPMed gnomAD
rs267606168 CA9976625	545	D>Y		No	ClinGen ESP ExAC TOPMed gnomAD
rs753090991 CA409820292	546	V>A		No	ClinGen ExAC gnomAD
CA9976622 rs753090991	546	V>D		No	ClinGen ExAC gnomAD
TCGA novel	546	V>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs144163164 CA9976621	547	V>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs144163164 CA409820294	547	V>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1448082435 CA409820302	548	A>G		No	ClinGen gnomAD
rs169758 VAR_057348 CA9976620	549	G>E		No	ClinGen UniProt ESP ExAC TOPMed dbSNP gnomAD
TCGA novel	550	S>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	550	S>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1332068983 CA409820317	551	D>G		No	ClinGen TOPMed gnomAD
CA9976617 rs144623440	551	D>N		No	ClinGen ESP ExAC TOPMed gnomAD
rs144623440 CA9976618	551	D>Y		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	552	D>=	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs770046700 CA9976615	552	D>K		No	ClinGen ExAC gnomAD
TCGA novel	552	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA

No associated diseases with P56180

5 regional properties for P56180

Type	Name	Position	InterPro Accession
domain	Tyrosine-specific protein phosphatases domain	313 - 381	IPR000387
domain	Tensin phosphatase, C2 domain	409 - 540	IPR014020
active_site	Protein-tyrosine phosphatase, active site	336 - 346	IPR016130
domain	Tensin-type phosphatase domain	228 - 404	IPR029023
domain	TPTE, protein tyrosine phosphatase-like catalytic domain	224 - 400	IPR045102

Functions

		Description
EC Number	3.1.3.48	Phosphoric monoester hydrolases
Subcellular Localization	Membrane; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

5 GO annotations of cellular component

Name	Definition
cell projection	A prolongation or process extending from a cell, e.g. a flagellum or axon.
cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
plasma membrane	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name	Definition
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity	Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-4,5-bisphosphate + phosphate.
protein tyrosine phosphatase activity	Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

8 GO annotations of biological process

Name	Definition
cell motility	Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.
dephosphorylation	The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
negative regulation of cell population proliferation	Any process that stops, prevents or reduces the rate or extent of cell proliferation.
phosphatidylinositol 3-kinase signaling	A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.
phosphatidylinositol dephosphorylation	The process of removing one or more phosphate groups from a phosphatidylinositol.
protein dephosphorylation	The process of removing one or more phosphoric residues from a protein.
regulation of protein kinase B signaling	Any process that modulates the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
signal transduction	The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

No homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins

10	20	30	40	50	60
MNESPDPTDL	AGVIIELGPN	DSPQTSEFKG	ATEEAPAKES	PHTSEFKGAA	RVSPISESVL
70	80	90	100	110	120
ARLSKFEVED	AENVASYDSK	IKKIVHSIVS	SFAFGLFGVF	LVLLDVTLIL	ADLIFTDSKL
130	140	150	160	170	180
YIPLEYRSIS	LAIALFFLMD	VLLRVFVERR	QQYFSDLFNI	LDTAIIVILL	LVDVVYIFFD
190	200	210	220	230	240
IKLLRNIPRW	THLLRLLRLI	ILLRIFHLFH	QKRQLEKLIR	RRVSENKRRY	TRDGFDLDLT
250	260	270	280	290	300
YVTERIIAMS	FPSSGRQSFY	RNPIKEVVRF	LDKKHRNHYR	VYNLCSERAY	DPKHFHNRVV
310	320	330	340	350	360
RIMIDDHNVP	TLHQMVVFTK	EVNEWMAQDL	ENIVAIHCKG	GTDRTGTMVC	AFLIASEICS
370	380	390	400	410	420
TAKESLYYFG	ERRTDKTHSE	KFQGVKTPSQ	KRYVAYFAQV	KHLYNWNLPP	RRILFIKHFI
430	440	450	460	470	480
IYSIPRYVRD	LKIQIEMEKK	VVFSTISLGK	CSVLDNITTD	KILIDVFDGL	PLYDDVKVQF
490	500	510	520	530	540
FYSNLPTYYD	NCSFYFWLHT	SFIENNRLYL	PKNELDNLHK	QKARRIYPSD	FAVEILFGEK
550
MTSSDVVAGS	D