P56067

PR
Gene name
cysM (cysK, HP_0107)
Protein name
Cysteine synthase
Names
CSase, O-acetylserine (thiol)-lyase, OAS-TL, O-acetylserine sulfhydrylase
Species
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
KEGG Pathway
hpy:HP_0107
EC number
2.5.1.47: Transferring alkyl or aryl groups, other than methyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

237-306 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for P56067

Entry ID Method Resolution Chain Position Source
6AHI X-ray 190 A A/B 1-306 PDB
AF-P56067-F1 Predicted AlphaFoldDB

No variants for P56067

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P56067

No associated diseases with P56067

2 regional properties for P56067

Type Name Position InterPro Accession
binding_site Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site 35 - 53 IPR001216
domain Tryptophan synthase beta chain-like, PALP domain 9 - 294 IPR001926

Functions

Description
EC Number 2.5.1.47 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
cystathionine beta-synthase activity Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O.
cysteine synthase activity Catalysis of the reaction: O3-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.

2 GO annotations of biological process

Name Definition
cysteine biosynthetic process The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.
cysteine biosynthetic process from serine The chemical reactions and pathways resulting in the formation of cysteine from other compounds, including serine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MMIITTMQDA IGRTPVFKFT NKDYPIPLNS AIYAKLEHLN PGGSVKDRLG QYLIGEGFKT
70 80 90 100 110 120
GKITSKTTII EPTAGNTGIA LALVAIKHHL KTIFVVPEKF STEKQQIMRA LGALVINTPT
130 140 150 160 170 180
SEGISGAIKK SKELAESIPD SYLPLQFENP DNPAAYYHTL APEIVQELGT NLTSFVAGIG
190 200 210 220 230 240
SGGTFAGTAR YLKERIPAIR LIGVEPEGSI LNGGEPGPHE IEGIGVEFIP PFFENLDIDG
250 260 270 280 290 300
FETISDEEGF SYTRKLAKKN GLLVGSSSGA AFVAALKEAQ RLPEGSQVLT IFPDVADRYL
SKGIYL