P55984
Gene name |
uppS (HP_1221) |
Protein name |
Isoprenyl transferase |
Names |
|
Species |
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) |
KEGG Pathway |
hpy:HP_1221 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
3 structures for P55984
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 2D2R | X-ray | 188 A | A/B | 2-233 | PDB |
| 2DTN | X-ray | 250 A | A/B | 2-233 | PDB |
| AF-P55984-F1 | Predicted | AlphaFoldDB |
No variants for P55984
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P55984 | |||||
No associated diseases with P55984
1 regional properties for P55984
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Di-trans-poly-cis-decaprenylcistransferase-like, conserved site | 176 - 193 | IPR018520 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| di-trans,poly-cis-decaprenylcistransferase activity | Catalysis of the reaction: di-trans-poly-cis-decaprenyl diphosphate + isopentenyl diphosphate = diphosphate + di-trans-poly-cis-undecaprenyl diphosphate. |
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
| manganese ion binding | Binding to a manganese ion (Mn). |
| polyprenyltransferase activity | Catalysis of the transfer of multiple prenyl groups from one compound (donor) to another (acceptor). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| polyprenol biosynthetic process | The chemical reactions and pathways resulting in the formation of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDNTLKHLAI | IMDGNGRWAK | LKNKARAYGH | KKGVKTLKDI | TIWCANHKLE | CLTLYAFSTE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NWKRPKSEVD | FLMKMLKKYL | KDERSTYLNN | NIRFRAIGDL | EGFSKELRDT | ILQLENDTRH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FKDFTQVLAL | NYGSKNELSR | AFKSLLESPP | SHINLLESLE | NEISNRLDTH | DLPEVDLLLR |
| 190 | 200 | 210 | 220 | 230 | |
| TGGEMRLSNF | LLWQSSYAEL | FFTPILWPDF | TPKDLENIIS | DFYKRVRKFG | ELKC |