P55977

PR
Gene name
nusA
Protein name
Transcription termination/antitermination protein NusA
Names
Species
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
KEGG Pathway
hpy:HP_1514
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

340-395 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P55977

Entry ID Method Resolution Chain Position Source
AF-P55977-F1 Predicted AlphaFoldDB

No variants for P55977

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P55977

No associated diseases with P55977

5 regional properties for P55977

Type Name Position InterPro Accession
domain S1 domain 137 - 201 IPR003029
domain Transcription termination factor NusA 5 - 365 IPR010213
domain Transcription factor NusA, N-terminal 5 - 120 IPR013735
domain RNA-binding domain, S1 135 - 201 IPR022967
domain KH domain, NusA-like 233 - 301 IPR025249

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

2 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
DNA-templated transcription termination The completion of transcription: the RNA polymerase pauses, the RNA-DNA hybrid dissociates, followed by the release of the RNA polymerase from its DNA template.
transcription antitermination Regulation of transcription by a mechanism that allows RNA polymerase to continue transcription beyond termination site(s).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEKISDLIEC IAYEKNLPKE MISKVIQGCL LKMAQNELDP LARYLVVEEN KQLQLIQLVE
70 80 90 100 110 120
VLEDGDERLV NDPSKYISLS KAKEMDPSVK IKDELSYSLS LESMKQGAIN RLFKDLQYQL
130 140 150 160 170 180
EKALEDSHFE AFQKRLNSVL MGQVILVDHN QNTFIEIEQQ FQGVLSMRHR IKGESFKVGD
190 200 210 220 230 240
SIKAVLTQVK RTKKGLLLEL SRTTPKMLEA LLELEVPEIK DKEIEIIHCA RIPGNRAKVS
250 260 270 280 290 300
FFSHNARIDP IGAAVGVKGV RINAISNELN KENIDCIEYS NVPEIYITLA LAPAKILSVE
310 320 330 340 350 360
IKKIPIEELN AEEKESIQER FIVNNHLQKA KVRLLDIEKS KAIGKGGVNV CLASMLTGYH
370 380 390
IEFETIPSVK ENAENESEKE TPKVGVEALE SLFKN