P55806

PR
Gene name
Protein name
NAD(P)(+)--arginine ADP-ribosyltransferase 1
Names
Mono(ADP-ribosyl)transferase 1, AT1
Species
Gallus gallus (Chicken)
KEGG Pathway
EC number
2.4.2.31: Pentosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

226-300 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P55806

Entry ID Method Resolution Chain Position Source
AF-P55806-F1 Predicted AlphaFoldDB

No variants for P55806

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P55806

No associated diseases with P55806

No regional properties for P55806

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P55806

Functions

Description
EC Number 2.4.2.31 Pentosyltransferases
Subcellular Localization
  • Secreted, extracellular space
  • The mature enzyme is probably secreted from granulocytes into the extracellular space
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytolytic granule A specialized secretory lysosome that is present in cells with cytolytic capability such as cytotoxic T lymphocytes and natural killer cells. Cytolytic granules mediate the storage and regulated excretion of lytic molecules for killing of target cells.
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

2 GO annotations of molecular function

Name Definition
NAD+ ADP-ribosyltransferase activity Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.
NAD+-protein-arginine ADP-ribosyltransferase activity Catalysis of the reaction: L-arginyl- + NAD+ = H+ + (ADP-D-ribosyl)-L-arginyl-

2 GO annotations of biological process

Name Definition
peptidyl-arginine ADP-ribosylation The transfer, from NAD, of ADP-ribose to peptidyl-arginine to form omega-N-(ADP-ribosyl)-L-arginine.
response to antibiotic Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MELLALRWVL LAGTLLSTSA ASSALQEGDL GSITVIMDMA LNSFDDQYLL CEDRMRARLQ
70 80 90 100 110 120
MENITEFSTN IAYAVTWRQA AAEWQKRWGH LARPMQLIRE QAIALLAYSA SSRMCTLFNE
130 140 150 160 170 180
ATRQGGRSHQ DYIHSYHFKT LHFFLTQALF ALRASQPRCY YVYRGVRGIR FMTQRGKSVR
190 200 210 220 230 240
FGQFTSTSLR KEATVNFGQD TLFVVKTCYG VPIKQFSFFP SEDEVLIPPF EVFEVINFSN
250 260 270 280 290 300
DRGSVKIQLH SKGKMSTHNC ELLKPQGGQW GRGHQEVGLG LSPGLSLPVL PCRRRVWEGL
310
GHREGDPIPA AV