P54894

PR
Gene name
argC2
Protein name
N-acetyl-gamma-glutamyl-phosphate reductase 2
Names
AGPR 2, N-acetyl-glutamate semialdehyde dehydrogenase 2, NAGSA dehydrogenase 2
Species
Nostoc sp (strain PCC 7120 / SAG 2582 / UTEX 2576)
KEGG Pathway
ana:all2498
EC number
1.2.1.38: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

126-195 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P54894

Entry ID Method Resolution Chain Position Source
AF-P54894-F1 Predicted AlphaFoldDB

No variants for P54894

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P54894

No associated diseases with P54894

2 regional properties for P54894

Type Name Position InterPro Accession
domain Semialdehyde dehydrogenase, NAD-binding 5 - 106 IPR000534
active_site N-acetyl-gamma-glutamyl-phosphate reductase, active site 112 - 128 IPR023013

Functions

Description
EC Number 1.2.1.38 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
N-acetyl-gamma-glutamyl-phosphate reductase activity Catalysis of the reaction: N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH + H+.
NAD binding Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.

1 GO annotations of biological process

Name Definition
arginine biosynthetic process The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNKPKIFIDG EAGTTGLQIY SRLNERDDIE LVSIAASKRK DADERAKLLN SVDVAILCLP
70 80 90 100 110 120
DDAAREAVSL VNSSQVKILD ASTAYRTAQG WVYGFPEMNP GQREKIANAQ FVSNPGCYPT
130 140 150 160 170 180
GFLACVRPLI AQGILPSSFP ITINAVSGYS GGGKSLIQKY DSFHEQQKGA TSDYPFGIYG
190 200 210 220 230 240
LQFGHKHVKE MHQHSGLASP PLFIPAVGDF EQGMLVQIPL PLWTLDNPPS GEEIHQAIAQ
250 260 270 280 290 300
YYQGEKFVQV APFKDPSLLR DGTFLDATAV NGTNIVQVFV FGNDNTKEAL LVARLDNLGK
310 320
GASGAAVQNL NIMLGLPEEL GL