P54810

PR
Gene name
phaA
Protein name
Acetyl-CoA acetyltransferase
Names
Acetoacetyl-CoA thiolase
Species
Paracoccus denitrificans
KEGG Pathway
EC number
2.3.1.9: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

208-323 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P54810

Entry ID Method Resolution Chain Position Source
AF-P54810-F1 Predicted AlphaFoldDB

No variants for P54810

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P54810

No associated diseases with P54810

5 regional properties for P54810

Type Name Position InterPro Accession
active_site Thiolase, active site 372 - 385 IPR020610
conserved_site Thiolase, conserved site 337 - 353 IPR020613
active_site Thiolase, acyl-enzyme intermediate active site 84 - 102 IPR020615
domain Thiolase, N-terminal 5 - 261 IPR020616
domain Thiolase, C-terminal 268 - 390 IPR020617

Functions

Description
EC Number 2.3.1.9 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
acetyl-CoA C-acetyltransferase activity Catalysis of the reaction: 2 acetyl-CoA = CoA + acetoacetyl-CoA.

1 GO annotations of biological process

Name Definition
poly-hydroxybutyrate biosynthetic process The chemical reactions and pathways resulting in the formation of poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTKAVIVSAA RTPVGSFLGS FANLPAHELG AIVLKAVVER AGIDPSEVSE TILGQVLTAA
70 80 90 100 110 120
QGQNPARQAH IKVGLPRESA AWVINQVCGS GLRTVALAAQ QVLLGDARIV VAGGQESMSL
130 140 150 160 170 180
APHAAYIAPG QKMGDMKMLD TMIKDGLWDA FNDYHMGTTA ENVAGKWEIS RAEQDQFAVA
190 200 210 220 230 240
SQNKAEAAQK AGKFADEIVP VTIKSRKGET VVDADEYIRH GATLEAMENV RPAFSKEGTV
250 260 270 280 290 300
TAGNASGLND GAAAVLVMTE DEAARRGLTP LARIASYATA GVDPQIMGTG PIPASRKALE
310 320 330 340 350 360
KAGWSVGDLD LVEANEAFAA QAIAVNRDMG WDPSIVNVNG GAIAIGHPIG ASGCRILNTL
370 380 390
LFEMQRRDAK KGLATLCIGG GMGVALCLER P