P54770

PR
Gene name
TYDC3
Protein name
Tyrosine/DOPA decarboxylase 3
Names
Species
Papaver somniferum (Opium poppy)
KEGG Pathway
EC number
4.1.1.25: Carboxy-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-100 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P54770

Entry ID Method Resolution Chain Position Source
AF-P54770-F1 Predicted AlphaFoldDB

No variants for P54770

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P54770

No associated diseases with P54770

1 regional properties for P54770

Type Name Position InterPro Accession
binding_site Pyridoxal-phosphate binding site 312 - 333 IPR021115

Functions

Description
EC Number 4.1.1.25 Carboxy-lyases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
5-hydroxy-L-tryptophan decarboxylase activity Catalysis of the reaction: 5-hydroxy-L-tryptophan + H+ = CO2 + serotonin.
L-dopa decarboxylase activity Catalysis of the reaction: L-dopa + H+ = CO2 + dopamine.
pyridoxal phosphate binding Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
tyrosine decarboxylase activity Catalysis of the reaction: L-tyrosine = tyramine + CO2.

1 GO annotations of biological process

Name Definition
cellular amino acid metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGSLNTEDVL EHSSAFGATN PLDPEEFRRQ GHMIIDFLAD YYRDVEKYPV RSQVEPGYLR
70 80 90 100 110 120
KRLPETAPYN PESIETILQD VTSEIIPGLT HWQSPNYYAY FPSSGSVAGF LGEMLSTGFN
130 140 150 160 170 180
VVGFNWMSSP AATELEGIVM DWFGKMLNLP KSYLFSGTGG GVLQGTTCEA ILCTLTAARD
190 200 210 220 230 240
RKLNKIGREH IGRLVVYGSD QTHCALQKAA QIAGINPKNF RAVKTFKANS FGLAASTLRE
250 260 270 280 290 300
VILEDIEAGL IPLFVCPTVG TTSSTAVDPI GPICEVAKEY EMWVHIDAAY AGSACICPEF
310 320 330 340 350 360
RHFIDGVEEA DSFSLNAHKW FFTTLDCCCL WVKDPSSLVK ALSTNPEYLR NKATESRQVV
370 380 390 400 410 420
DYKDWQIALI RRFRSMKLWM VLRSYGVTNL RNFLRSHVRM AKTFEGLVGA DRRFEITVPR
430 440 450 460 470 480
TFAMVCFRLL PPTTVKVCGE NGVHQNGNGV IAVLRNENEE LVLANKLNQV YLRQVKATGS
490 500 510 520 530
VYMTHAVVGG VYMIRFAVGS TLTEERHVIH AWEVLQEHAD LILSKFDEAN FSS