P54737

PR
Gene name
pkn5
Protein name
Serine/threonine-protein kinase pkn5
Names
Species
Myxococcus xanthus
KEGG Pathway
EC number
2.7.11.1: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

75-242 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

261-286 (Activation loop from InterPro)

Target domain

9-379 (Protein kinase domain)

Relief mechanism

Assay

References

Autoinhibited structure

Activated structure

1 structures for P54737

Entry ID Method Resolution Chain Position Source
AF-P54737-F1 Predicted AlphaFoldDB

No variants for P54737

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P54737

No associated diseases with P54737

3 regional properties for P54737

Type Name Position InterPro Accession
domain Protein kinase domain 9 - 379 IPR000719
domain Serine-threonine/tyrosine-protein kinase, catalytic domain 11 - 369 IPR001245
active_site Serine/threonine-protein kinase, active site 240 - 252 IPR008271

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

1 GO annotations of biological process

Name Definition
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPLKVIGPYR VLETLGSGGA GTVYRALDRR TTDEVALKLL SAGPARDARA ARRLAREFDT
70 80 90 100 110 120
LVDLSHPNVV KVFESGVHQG VPYLAMELIE GLTLRHYLDL SSGDRQTPPG SHTPRSPLSV
130 140 150 160 170 180
LRTADDDFGP LSRSFSDSMD DSEDSPFDGT FGLEAFAEEA PSEDLESFAS SASPHVGIGS
190 200 210 220 230 240
DDSLEGFDLP PPMPRPAEPE EEPGRVVREE DLNRPERMGR LKDAMLQICE ALAYIHGHGL
250 260 270 280 290 300
VHRDLKPSNI MVDDDRQVRL MDFGLAKFLA DDAAITEAGK LVGTYRYMAP EQILGEPLDG
310 320 330 340 350 360
RADLYSLGVI LYELLSGRPP FDAKTPHELW RQVLETEPPP VLALNLHGDP QLARVAHRLI
370
RKEPDDRFQT AEEVYEALSE