P54718

PR
Gene name
yfiB (BSU08210)
Protein name
Uncharacterized ABC transporter ATP-binding protein YfiB
Names
Species
Bacillus subtilis (strain 168)
KEGG Pathway
bsu:BSU08210
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

281-352 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P54718

Entry ID Method Resolution Chain Position Source
AF-P54718-F1 Predicted AlphaFoldDB

No variants for P54718

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P54718

No associated diseases with P54718

4 regional properties for P54718

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 330 - 563 IPR003439
domain AAA+ ATPase domain 356 - 540 IPR003593
domain ABC transporter type 1, transmembrane domain 17 - 298 IPR011527
conserved_site ABC transporter-like, conserved site 468 - 482 IPR017871

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ABC-type transporter activity Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATPase-coupled transmembrane transporter activity Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source.

1 GO annotations of biological process

Name Definition
transmembrane transport The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQKALSFLKP YSLLAGIALI LMLTELAVEL MQPLLIAKII DDGILKQDLR HVWIWGTVMI
70 80 90 100 110 120
GLTVLSFAAG MLNSFYAAHV SQSFSYDTRK GLFQKIQSFS YSTFGQFSSS SYITRLTNDV
130 140 150 160 170 180
TQVQNMIFMS LRFMLRAPLM IAGGIVLSLA VNVKLGFFLL VTIPILILFL LWVLRKGGAL
190 200 210 220 230 240
FRSVQKRLDQ VNTIMQENLI AIKLIKALLR GSHEVKRFIK ANTRLMEKTV SAFQLVEFTM
250 260 270 280 290 300
PVLMLLMNLC ILLILWAGSY SITSGSTQVG DVVAIINYAT RITGALSMFP FLIMIFTRAK
310 320 330 340 350 360
ASGDRIGEVL ETEGDEREEG TISDRLSGRI EFQHVSFRYP EMDREALRNV SFSAKPRETI
370 380 390 400 410 420
AILGATGSGK STLFQLIPRL YQPDSGRIYI DEKPVQDIPA EGLRRQIGYV PQEVLLFSGT
430 440 450 460 470 480
IKENIAWGKE NASLDEIMDA AKLAQIHETI LKLPNGYDTV LGQRGVNLSG GQKQRISIAR
490 500 510 520 530 540
ALIRKPAILL LDDSTSALDL QTEAKLLEAI STYHCTTLII TQKITTAMKA DQILLLEDGE
550 560 570
LIEKGTHSEL LSESQLYKRI YESQFGREGS ESC