P54649

PR
Gene name
htpG
Protein name
Chaperone protein HtpG
Names
Heat shock protein HtpG, High temperature protein G
Species
Aggregatibacter actinomycetemcomitans (Actinobacillus actinomycetemcomitans) (Haemophilus actinomycetemcomitans)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

76-148 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P54649

Entry ID Method Resolution Chain Position Source
AF-P54649-F1 Predicted AlphaFoldDB

No variants for P54649

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P54649

No associated diseases with P54649

3 regional properties for P54649

Type Name Position InterPro Accession
domain Histidine kinase/HSP90-like ATPase 28 - 185 IPR003594
conserved_site Heat shock protein Hsp90, conserved site 26 - 35 IPR019805
domain Heat shock protein Hsp90, N-terminal 6 - 209 IPR020575

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
ATP-dependent protein folding chaperone Binding to a protein or a protein-containing complex to assist the protein folding process, driven by ATP hydrolysis.
unfolded protein binding Binding to an unfolded protein.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSTNQETRGF QSEVKQLLQL MIHSLYSNKE IFLRELISNA SDAADKLRFK ALSNPDLYAG
70 80 90 100 110 120
DGELRVCISF DSEKGTLTVS DNGIGMTREQ VIDHLGTIAK SGTKEFLAAL GSDQAKDSQL
130 140 150 160 170 180
IGQFGVGFYS AFIVADKVTV KTRAAGEPAD KGVLWESAGE GDYTVADIEK KSRGTDVILH
190 200 210 220 230 240
LRDDEKEFLN EWRLRGIIGK YSDHIGLPVE MLTKEYEDEG KEIGEKWEKI NKSDALWTRS
250 260 270 280 290 300
KNEISDEEYK EFYKHLSHDF ADPLLWAHNK VEGNQEYTSL LYVPSKAPWD LFNREHKHGL
310 320 330 340 350 360
KLYVQRVFIM DDAEQFMPNY LRFMRGLIDS NDLPLNVSRE ILQDNKVTAA LRKALTKRSL
370 380 390 400 410 420
QMLEKLAKDD AEKYQQFWKE FGLVLKEGPA EDFANKEAIA KLLRFASTHN DSSEQNVSLE
430 440 450 460 470 480
DYVSRMKEGQ KAIYYITADS YVAARNSPHL ELFNKKGIEV LLLSDRIDEW MLSYLTEFDG
490 500 510 520 530 540
KPLQSITKAD LDLGDLADKE AEEQKAQDES FGSFVERVKT LLGGRVKEVR LTHRLTDTPA
550 560 570 580 590 600
VVSTDNDQMT TQMAKLFAAA GQPVPEVKYT FELNPEHHLV KKVAEIADEA QFADWVELLL
610 620
EQAMLAERGS LENPAAFIKR INKLLG