P54475

PR
Gene name
cshB
Protein name
DEAD-box ATP-dependent RNA helicase CshB
Names
Species
Bacillus subtilis (strain 168)
KEGG Pathway
bsu:BSU25140
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

354-438 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P54475

Entry ID Method Resolution Chain Position Source
AF-P54475-F1 Predicted AlphaFoldDB

No variants for P54475

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P54475

No associated diseases with P54475

4 regional properties for P54475

Type Name Position InterPro Accession
domain Helicase, C-terminal 235 - 385 IPR001650
domain DEAD/DEAH box helicase domain 28 - 195 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 23 - 223 IPR014001
domain RNA helicase, DEAD-box type, Q motif 4 - 32 IPR014014

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Cytoplasm, nucleoid
  • Shows transcription-dependent localization at subcellular sites surrounding the nucleoid
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
bacterial nucleoid The region of a bacterial cell to which the DNA is confined.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

5 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.
RNA strand annealing activity An activity that facilitates the formation of a complementary double-stranded RNA molecule.

3 GO annotations of biological process

Name Definition
response to cold Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
ribosomal large subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.
RNA catabolic process The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKETKFELYE LKPFIIDAVH RLGFYEPTDI QKRLIPAVLK KESVIGQSQT GTGKTHAYLL
70 80 90 100 110 120
PLLNKIDPAK DVVQVVITAP TRELANQIYQ EALKITQGEE GSQIRSKCFI GGTDKQKSID
130 140 150 160 170 180
KLKIQPHLVV GTPGRIADLI KEQALSVHKA ESLVIDEADL MLDMGFLADV DYIGSRMPED
190 200 210 220 230 240
LQMLVFSATI PEKLKPFLKK YMENPKYAHV EPKQVTAAKI EHILIPSKHR DKDKLLFDIM
250 260 270 280 290 300
SHLNPYLGIV FANTKNTADH IAQYLTGKGM KIGLLHGGLT PRERKKVMKQ INDLEFTYII
310 320 330 340 350 360
ATDLAARGID IKGVSHVINY ELPDDLDFYV HRVGRTARAG SSGQAMTIYE LTDEDALVRL
370 380 390 400 410 420
EKMGIEFEYL ELEKGEWKKG DDRQRRKKRK KTPNEADEIA HRLVKKPKKV KPGYKKKMSY
430
EMEKIKKKQR RNQSKKRK