Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

2 structures for P54375

Entry ID Method Resolution Chain Position Source
2RCV X-ray 160 A A/B/C/D/E/F/G/H 1-200 PDB
AF-P54375-F1 Predicted AlphaFoldDB

No variants for P54375

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P54375

No associated diseases with P54375

3 regional properties for P54375

Type Name Position InterPro Accession
domain Manganese/iron superoxide dismutase, N-terminal 3 - 90 IPR019831
domain Manganese/iron superoxide dismutase, C-terminal 97 - 195 IPR019832
binding_site Manganese/iron superoxide dismutase, binding site 164 - 171 IPR019833

Functions

Description
EC Number 1.15.1.1 Acting on superoxide as acceptor
Subcellular Localization
  • Cytoplasm
  • Secreted
  • Present in the cytoplasm early in growth, as cells become stationary protein also accumulates in the medium; secreted protein is not processed (PubMed:21856851)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
superoxide dismutase activity Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAYELPELPY AYDALEPHID KETMTIHHTK HHNTYVTNLN KAVEGNTALA NKSVEELVAD
70 80 90 100 110 120
LDSVPENIRT AVRNNGGGHA NHKLFWTLLS PNGGGEPTGA LAEEINSVFG SFDKFKEQFA
130 140 150 160 170 180
AAAAGRFGSG WAWLVVNNGK LEITSTPNQD SPLSEGKTPI LGLDVWEHAY YLNYQNRRPD
190 200
YISAFWNVVN WDEVARLYSE AK