Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P54148

Entry ID Method Resolution Chain Position Source
AF-P54148-F1 Predicted AlphaFoldDB

No variants for P54148

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P54148

No associated diseases with P54148

3 regional properties for P54148

Type Name Position InterPro Accession
domain HAMP domain 486 - 513 IPR003660
conserved_site Ammonium transporter, conserved site 160 - 185 IPR018047
domain Ammonium transporter AmtB-like domain 7 - 402 IPR024041

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
ammonium transmembrane transporter activity Enables the transfer of ammonium from one side of a membrane to the other. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.

3 GO annotations of biological process

Name Definition
ammonium homeostasis Any biological process involved in the maintenance of an internal steady state of ammonium.
ammonium transmembrane transport The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+.
signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTSIDTLWLL LCAGLVFFMQ AGFMCLESGL TRSKNSINVA IKNFADFGIS VALFWSFGFS
70 80 90 100 110 120
IMFGLSQGGW WGTGYSFVDV GGEPTLAVFF LFQAMFCGTA TTIISGAAAE RLKFSAYLLV
130 140 150 160 170 180
AGLASGLIYP LFGDWAWNGL ATVAGIETTG GWLENLGFRD FAGSTVVHSV GAWIGLATIL
190 200 210 220 230 240
VVGPRQGRFP KTGKTLKIQG SNMPFSVLGT LILWFGWLGF NGGSTFGLTP EVPGIMVNTV
250 260 270 280 290 300
LAGVGGMLMA GLISLLQDKM IQVEPLMNGS LAGLVAITAS ANVVMTPIAM VIGATGSAIA
310 320 330 340 350 360
YLVGKKMLHW GVDDAVDAVA VHGGAGVWGT LCVGLFGQLP LVDTGLNRWQ QCGVQLLGIG
370 380 390 400 410 420
VCTLWAFGLA WVFLTLLNRV FALRISPEDE EIGLNVSEHQ ATTETYELFQ VMDRQAKTHD
430 440 450 460 470 480
LSLRVPVNPF TEVGHIAGRY NQVMDAFEAR HHRSVEDLAQ IYYVTAAIAA AIENNSFKAD
490 500 510 520 530 540
QLGLEEVTNR ADELGALART IQQMAEMLQQ RDQELIAVKQ QLVLQQQKQH HGNGESVDLS
P