P53937

PR
Gene name
SWS2 (YNL081C, N2322)
Protein name
37S ribosomal protein SWS2, mitochondrial
Names
Mitochondrial small ribosomal subunit protein uS13m, Sick without securin protein 2
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YNL081C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

65-143 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

9 structures for P53937

Entry ID Method Resolution Chain Position Source
5MRC EM 325 A MM 2-121 PDB
5MRE EM 375 A MM 2-121 PDB
5MRF EM 497 A MM 2-121 PDB
8D8K EM 313 A M 1-143 PDB
8D8L EM 260 A M 1-143 PDB
8OM2 EM 257 A M 1-143 PDB
8OM3 EM 287 A M 1-143 PDB
8OM4 EM 232 A M 1-143 PDB
AF-P53937-F1 Predicted AlphaFoldDB

3 variants for P53937

Variant ID(s) Position Change Description Diseaes Association Provenance
s14-476500 41 F>L No SGRP
s14-476220 134 P>L No SGRP
s14-476208 138 S>F No SGRP

No associated diseases with P53937

1 regional properties for P53937

Type Name Position InterPro Accession
conserved_site Ribosomal protein S13, conserved site 89 - 102 IPR018269

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
  • Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
mitochondrial small ribosomal subunit The smaller of the two subunits of a mitochondrial ribosome.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
small ribosomal subunit The smaller of the two subunits of a ribosome.

2 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

1 GO annotations of biological process

Name Definition
mitochondrial translation The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVVHILGKGF KGKEVIKIAL ASKFYGIGKT TAEKICSKLG FYPWMRMHQL SEPQIMSIAS
70 80 90 100 110 120
ELSTMTIEGD ARAIVKDNIA LKRKIGSYSG MRHTLHLPVR GQHTRNNAKT ARKLNKIDRR
130 140
GIHTFSQAKV QHNPSLWSCI FGK