P53768

PR
Gene name
HAP2 (KLLA0A00891g)
Protein name
Transcriptional activator HAP2
Names
Species
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
KEGG Pathway
kla:KLLA0_A00891g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

212-300 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P53768

Entry ID Method Resolution Chain Position Source
AF-P53768-F1 Predicted AlphaFoldDB

No variants for P53768

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P53768

No associated diseases with P53768

1 regional properties for P53768

Type Name Position InterPro Accession
active_site Phenylalanine/histidine ammonia-lyases, active site 249 - 265 IPR022313

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
CCAAT-binding factor complex A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; functions as both an activator and a repressor, depending on its interacting cofactors. Typically trimeric consisting of NFYA, NFYB and NFYC subunits. In Saccharomyces, it activates the transcription of genes in response to growth in a nonfermentable carbon source and consists of four known subunits: HAP2, HAP3, HAP4 and HAP5.

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPTELITYEQ NFSSGVDAEN DYPPLDSGMG SFQVSELERQ GDSHKRSNDE ISELRDETLN
70 80 90 100 110 120
GREKKLRQSE SISRNSTGNA QVEAIPHHSI NVDQSDNLLS EQENPTKVYL YDDPHLENDP
130 140 150 160 170 180
QQRQEESDAN GIMEKLTDDN SMKQVSNAKT SLETAQFLET SNSMELQRTK PHDMNIISPS
190 200 210 220 230 240
EPLEQPFYVN AKQYYRILKR RYARAKLEEN LKISRERRPY LHESRHKHAM RRPRGQGGRF
250 260 270 280 290
LTAAEMAEMK RKEEEGTDND SFLQEHVPKM NVLPQQLPGP VKDNNNEKSD EKPVAKEASN