P53681

PR
Gene name
CRK
Protein name
CDPK-related protein kinase
Names
PK421
Species
Daucus carota (Wild carrot)
KEGG Pathway
EC number
2.7.11.1: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-167 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

296-318 (Activation loop from InterPro)

Target domain

148-410 (Protein kinase domain)

Relief mechanism

Assay

References

Autoinhibited structure

Activated structure

1 structures for P53681

Entry ID Method Resolution Chain Position Source
AF-P53681-F1 Predicted AlphaFoldDB

No variants for P53681

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P53681

No associated diseases with P53681

3 regional properties for P53681

Type Name Position InterPro Accession
domain Protein kinase domain 148 - 410 IPR000719
active_site Serine/threonine-protein kinase, active site 272 - 284 IPR008271
binding_site Protein kinase, ATP binding site 154 - 180 IPR017441

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

1 GO annotations of biological process

Name Definition
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGICVSKPSP EPDLHNHHTS IPVNDTSLPP QDNSIPPKDI AIPAQDNNKP PGKKSPFLPF
70 80 90 100 110 120
YSPSPAHFLF SKKSPAVGSP AAGSSNSTPK RLFPFPPPSP AKHIKAAWAR RHGSVKPNEA
130 140 150 160 170 180
AIPENNEVDG GAGLDKSFGF SKKFGSKFEV GEEVGRGHFG YTCRAKFKKG EFKGQDVAVK
190 200 210 220 230 240
VIPKAKMTTA IAIEDVRREV KILRALTGHN NLVQFYDAFE DHTNVYVVME LCEGGELLDR
250 260 270 280 290 300
ILSRGGKYTE DDAKAVMIQI LNVVAFCHLQ GVVHRDLKPE NFLFKSKDED SQLKAIDFGL
310 320 330 340 350 360
SDYVKPDERL NDIVGSAYYV APEVLHRSYS TEADVWSIGV ISYILLCGSR PFWARTESGI
370 380 390 400 410 420
FRAVLKANLS FDEPPWPSVS SEAKDFVKRL LNKDPRKRMT AAQALCHSWI KNSNDIKFPL
430 440 450 460 470 480
DILVFKLMKV YMRSSPLRKA ALRALSKTLT VDELFYLKEQ FVLLEPTKNG TISLENIKQA
490 500 510 520 530 540
LMRNSTDAMK DSRVLDLLVS LNALQYRRMD FEEFCAAALS VHQLEALDRW EQHARCAYDL
550 560 570 580 590 600
FEKDGNRAIM IEELASELGL GPSIPVHAVL HDWIRHTDGK LSFLGYVKLL HGVSTRAIAK
AQ