P53526
Gene name |
echA12 (ML1241, B1170_C2_224, MLCB1610.01) |
Protein name |
Probable enoyl-CoA hydratase echA12 |
Names |
|
Species |
Mycobacterium leprae (strain TN) |
KEGG Pathway |
mle:ML1241 |
EC number |
4.2.1.17: Hydro-lyases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P53526
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P53526-F1 | Predicted | AlphaFoldDB |
No variants for P53526
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P53526 | |||||
No associated diseases with P53526
1 regional properties for P53526
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Enoyl-CoA hydratase/isomerase, conserved site | 124 - 144 | IPR018376 |
Functions
| Description | ||
|---|---|---|
| EC Number | 4.2.1.17 | Hydro-lyases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| enoyl-CoA hydratase activity | Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2-enoyl-CoA + H2O. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| fatty acid metabolic process | The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSQTDASCTI | AELPYRSVTD | LVVLDFPRPE | VALITLNRPG | RMNSMALDLM | KSLKQVLKRI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TYDHSVRVVV | LTGAGRGFCS | GADQKFTAPV | PQVEGLTQPV | RALRAMELLE | EVILALRRLH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QPVIAAINGP | AIGGGLCLAL | AADVRVASTR | AYFRAAGINN | GLSASELGLS | YLLPRAVGSS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RAFEIMLSGR | DVGAEEAEQI | GLVSYRVSDD | RLLDTCYSIA | ARMATFSRSG | TELTKRALWG |
| 250 | 260 | 270 | 280 | 290 | |
| GLDAASLDKH | MQSESLAQLF | IALHTSNFEE | AAAPCTEKRP | TVLVDARGCA | TSPG |