Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P53316

Entry ID Method Resolution Chain Position Source
AF-P53316-F1 Predicted AlphaFoldDB

15 variants for P53316

Variant ID(s) Position Change Description Diseaes Association Provenance
s07-993445 28 A>T No SGRP
s07-993313 72 D>N No SGRP
s07-993201 109 R>K No SGRP
s07-993189 113 V>A No SGRP
s07-992737 264 S>P No SGRP
s07-992467 354 S>G No SGRP
s07-992390 379 M>I No SGRP
s07-992329 400 T>S No SGRP
s07-992203 442 V>I No SGRP
s07-991922 535 S>R No SGRP
s07-991902 542 L>P No SGRP
s07-991762 589 S>P No SGRP
s07-991562 655 N>K No SGRP
s07-991240 763 A>T No SGRP
s07-991207 774 S>G No SGRP

No associated diseases with P53316

3 regional properties for P53316

Type Name Position InterPro Accession
domain RNA recognition motif domain 195 - 273 IPR000504-1
domain RNA recognition motif domain 295 - 418 IPR000504-2
domain RNA recognition motif domain 540 - 638 IPR000504-3

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytoplasmic stress granule A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.

1 GO annotations of molecular function

Name Definition
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNIAEEPSDE VISSGPEDTD ICSQQTSASA EAGDQSIKIE RKTSTGLQLE QLANTNLLTI
70 80 90 100 110 120
RIKWQLQEEE DDHCNSRITD QIMDTIQHYK GISVNNSDTE TYEFLPDTRR LQVLEQNKDI
130 140 150 160 170 180
YLYEHGSQEY EKSYKDNEEE DDWRYDTVLQ AQFKYPKSLE NACTDISELL KSEPIGQHID
190 200 210 220 230 240
KWSIGVNKHA LTYPGNIFVG GIAKSLSIGE LSFLFSKYGP ILSMKLIYDK TKGEPNGYGF
250 260 270 280 290 300
ISYPLGSQAS LCIKELNGRT VNGSTLFINY HVERKERERI HWDHVKENNN DDNFRCLFIG
310 320 330 340 350 360
NLPYHNPEKV ETLITPKEVI EVIKKELSKK FPDFDIISYY FPKRSNTRSS SSVSFNEEGS
370 380 390 400 410 420
VESNKSSNNT NGNAQDEDML KGYGFIKLIN HEQALAAIET FNGFMWHGNR LVVNKAVQHK
430 440 450 460 470 480
VYNNHNSHDR HPSISNHNDM EVLEFANNPM YDYNNYTYDR YYFNNNKNGN SNDTSNVRYF
490 500 510 520 530 540
DSVRSTPVAE KMDLFYPQRE SFSEGRGQRV PRFMGNKFDM YQYPSTSYSL PIPMSNQQES
550 560 570 580 590 600
NLYVKHIPLS WTDEDLYDFY KSFGEIISVK VITVGGSKNK YRQQSNDSSS DNDLPVGSSR
610 620 630 640 650 660
GYGFVSFESP LDAAKAILNT DGYQVSKDQV LSVSFAQKRG NLSSSDDDDQ SQTDNSSKFQ
670 680 690 700 710 720
NFQPHNDYHK AYPTKYNKKF INALMTQNQS QQQVSRENYF IPLQYPNTNT KPVNSYNLIS
730 740 750 760 770 780
ANQNNANWMM PMFPSFGFIP QVPPVPYIIP PQNPAANHIP IMANGSNEEE EFSSGDYSMD
Y