P53217
Gene name |
YGR026W |
Protein name |
Uncharacterized membrane protein YGR026W |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YGR026W |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P53217
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P53217-F1 | Predicted | AlphaFoldDB |
3 variants for P53217
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s07-533332 | 115 | N>S | No | SGRP | |
| s07-533751 | 255 | V>I | No | SGRP | |
| s07-533763 | 259 | F>L | No | SGRP |
No associated diseases with P53217
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cell periphery | The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures. |
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| endoplasmic reticulum tubular network organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section. |
| membrane organization | A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9V447 | Kr-h2 | Krueppel homolog 2 | Drosophila melanogaster (Fruit fly) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAKTIKVIRK | KDPKKKNLSD | PLAKQKLVWK | IGHVLTLVFG | LLFSITYFYH | VLIFFKYRSW |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KWLFLRVNKN | YSFIQSKRWY | MKLLSWSPQV | MYRLSLIGVF | MSESVTMQQN | WVGLNPTWND |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LLSSENFHTL | LIACLWFFGG | GKSFYKILPY | MILSYLHLTK | MNYELNANKE | EKIPLTPKDR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KMLHLLAYSE | LLVILALTLD | TILFKTGTSG | FMLVIYVGIY | WLRLNFSPYA | QVAVLELLVK |
| 250 | 260 | 270 | |||
| FEKYVPKKYR | DKWQVIKNFI | YMKMKEHEKR | TEEVARYA |