P53120
Gene name |
YGL140C |
Protein name |
Uncharacterized membrane protein YGL140C |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YGL140C |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P53120
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P53120-F1 | Predicted | AlphaFoldDB |
11 variants for P53120
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s07-244762 | 86 | I>V | No | SGRP | |
| s07-244174 | 282 | V>I | No | SGRP | |
| s07-243908 | 370 | I>M | No | SGRP | |
| s07-243597 | 474 | K>R | No | SGRP | |
| s07-243563 | 485 | K>N | No | SGRP | |
| s07-242328 | 897 | A>V | No | SGRP | |
| s07-241716 | 1101 | G>E | No | SGRP | |
| s07-241713 | 1102 | N>I | No | SGRP | |
| s07-241701 | 1106 | Q>L | No | SGRP | |
| s07-241530 | 1163 | N>S | No | SGRP | |
| s07-241513 | 1169 | T>A | No | SGRP |
No associated diseases with P53120
1 regional properties for P53120
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Putative ER transporter, 6TM, N-terminal | 10 - 437 | IPR018823 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSLKSKLTKI | QKLWLYYFPC | DRILAKRICK | STVNTTVAFI | FCLIPKITAH | LGAAPAMLPM |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ISVIVHPGRR | VGGTIHGAIY | CITGLIFGLA | YAIFGRFLAQ | RCLGSSWHEL | TEAQQHVLHY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KRYEAGLAIL | AVFEVIMLFF | HGWMRSVSHY | YFGIVFPLFV | VVHFAFMDPL | NETAGTIAKA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YSTPFYLGIA | MSIFWNLVLF | PEWGTTYLGN | TTIDAMNELH | KSIDYSINFF | IAVDPHNSSQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LYSRDPVSLG | KLLKMKSLIS | SKVNNCRVVL | HECIYEFTYA | YVSPTKLKPI | ISTLENLTVF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| INGLVNTCQL | EFILLARHDN | KLRPDDVAAL | TLPKNKEISF | ANAEKLLKVI | DKLHPVIYSL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| HRTMSECMYI | AKLVLAHAFD | VKVSRVHSCS | MFKDGNFPTF | SNNANNLPND | VDIQNKINDL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KQALEECKAK | FKSEMLSFDI | DIMSPSDEMF | LLSSFLLNFR | QTADSTLVIM | ESVKDILVKR |
| 490 | 500 | 510 | 520 | 530 | 540 |
| QIQEKKGWLR | GKRLWFLVLT | NYETFSIWLK | GDRNSVTEND | TLKGTFNGNT | NGFAHDTVIR |
| 550 | 560 | 570 | 580 | 590 | 600 |
| RPDYEENELL | SQKVSSNKNI | VKDDASLDLP | MTSEPKGNSS | STSDTSSSPL | TLTKTTTFGT |
| 610 | 620 | 630 | 640 | 650 | 660 |
| NRTSRRQGRF | SFMSMLISID | KFCEVSHPHF | RFGFQVAIAL | MLASFPMFIP | KTRQWYIDYR |
| 670 | 680 | 690 | 700 | 710 | 720 |
| GTWIGFVCIL | CLEPSVGGTF | WVFFLRAVGV | IFGAAWGYLS | YVAAVNQTNP | YLETVITVFG |
| 730 | 740 | 750 | 760 | 770 | 780 |
| AIPGFYYLLG | TPYVKAAIIE | IISIYIVMLA | AILPSQDDIL | TSFAKRCLAV | GYGGGVALIV |
| 790 | 800 | 810 | 820 | 830 | 840 |
| QVFFFPLKAR | EQLNEEISFV | CGCISEMELL | YATGLEGEQV | ASSMSEEKYK | KIEKISKSAK |
| 850 | 860 | 870 | 880 | 890 | 900 |
| EALARATAYK | GLTRQEPRLK | GEYTELENVF | TQVIFIQKQI | IERIDTISLL | RKQNGSAVIE |
| 910 | 920 | 930 | 940 | 950 | 960 |
| EFNSVVYPYR | RQMVGSISCL | MRALQEAFIN | KTPLPQFLPS | ARIAHRRLIN | KVRQTLRIRY |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| PGQISNLSDK | ARKPNEGDYA | DGKDEDDDDN | EGLVMKMNRR | GQANTTANPH | EYVLKEKFLS |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| WNASSAASEE | IIEYIEELLN | LTKILVGVNE | FKYGFLSRPL | YEDWAAEAVT | GFDNFINGKS |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| NPMNTRRNRT | PFDGTSIISE | GNESLQSTNS | NESQISPDST | RSYEPECPVA | YEKNDNPAAL |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| NLLRIASHKA | GQNADGLPKT | FRNRAFSITS | TSGQLSSLSR | HSTLGNADPN | YLNDDDESSD |
| 1210 | |||||
| DDLPLALKMV | LSHMKEKKD |