P53052

PR
Gene name
cpdB
Protein name
2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase
Names
Species
Yersinia enterocolitica
KEGG Pathway
EC number
3.1.3.6: Phosphoric monoester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-49 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P53052

Entry ID Method Resolution Chain Position Source
AF-P53052-F1 Predicted AlphaFoldDB

No variants for P53052

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P53052

No associated diseases with P53052

5 regional properties for P53052

Type Name Position InterPro Accession
domain Calcineurin-like phosphoesterase domain, ApaH type 29 - 264 IPR004843
conserved_site 5'-Nucleotidase, conserved site 29 - 41 IPR006146-1
conserved_site 5'-Nucleotidase, conserved site 114 - 125 IPR006146-2
domain 5'-Nucleotidase, C-terminal 360 - 554 IPR008334
domain CpdB, N-terminal metallophosphatase domain 29 - 326 IPR041827

Functions

Description
EC Number 3.1.3.6 Phosphoric monoester hydrolases
Subcellular Localization
  • Periplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
periplasmic space The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).

4 GO annotations of molecular function

Name Definition
2',3'-cyclic-nucleotide 2'-phosphodiesterase activity Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 3'-phosphate.
3'-nucleotidase activity Catalysis of the reaction: a 3'-ribonucleotide + H2O = a ribonucleoside + phosphate.
metal ion binding Binding to a metal ion.
nucleotide binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.

1 GO annotations of biological process

Name Definition
nucleotide catabolic process The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFKRPLTLSL LASLIALTTS TAQAATVDLR VLETTDLHSN MMDFDYYKDK PTEKFGLVRT
70 80 90 100 110 120
ASLIEAARQQ ATNSVLVDNG DLIQGSPLGD YMAAKGLKAG EIHPVYKAMN TLDYAVGNIG
130 140 150 160 170 180
NHEFNYGLDY LKKSLAGAKF PYVNANVIDV KTGKPLFQPY LIVDTPVKDR DGKNHNLRIG
190 200 210 220 230 240
YIGFGPPQVM IWDKANLTGK VTVDDITETA KKWVPEMRKQ GANLVVAIPH SGLSSDPYKT
250 260 270 280 290 300
MAENSVYYLS QVPGIDAIMF GHAHAVFPSK DFATIKGADI AQGTLNGIPA VMPGQWGDHL
310 320 330 340 350 360
GVVDFVLNND QGQWQVTQAK AEARPIFDKA TQKSLAAENA NLMKVLAADH QGTRDFVSQP
370 380 390 400 410 420
IGTASDNMYS YLSLIQDDPT VQIVNNAQRA YTEHFIQGDP DLADLPVLSA AAPFKAGGRK
430 440 450 460 470 480
NDPASFVEVE KGELTFRNAA DLYLYPNTLV VVKASGADVK QWLECSAAQF NQIDVNSSKP
490 500 510 520 530 540
QSLINWDSFR TYNFDVIDGV NYEIDVSQPA RYDGECALIN DKAERIKNLT FNGKPIDPQA
550 560 570 580 590 600
TFLIGTNNYR AYSGKFAGTG DSHIAFASPD ENRAVLSAYI SAETKKHGQV TPQADNNWRL
610 620 630 640 650
ATLNSQQPLD IRFETSPSTK AAEFIKQKAQ YPMKAMGTDE IGFAVFKIDL QK