P52938

PR
Gene name
spo0A
Protein name
Stage 0 sporulation protein A homolog
Names
Species
Clostridioides difficile (Peptoclostridium difficile)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

104-174 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P52938

Entry ID Method Resolution Chain Position Source
AF-P52938-F1 Predicted AlphaFoldDB

No variants for P52938

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P52938

No associated diseases with P52938

2 regional properties for P52938

Type Name Position InterPro Accession
domain Signal transduction response regulator, receiver domain 9 - 128 IPR001789
domain Sporulation initiation factor Spo0A, C-terminal 163 - 266 IPR014879

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
calcium ion binding Binding to a calcium ion (Ca2+).
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.

4 GO annotations of biological process

Name Definition
detection of stimulus The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal.
phosphorelay signal transduction system A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
regulation of sporulation resulting in formation of a cellular spore Any process that modulates the frequency, rate or extent of spore formation.
sporulation resulting in formation of a cellular spore The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGGFLVEKIK IVLADDNKDF CQVLKEYLSN EDDIDILGIA KDGIEALDLV KKTQPDLLIL
70 80 90 100 110 120
DVIMPHLDGL GVIEKLNTMD IPKMPKIIVL SAVGQDKITQ SAINLGADYY IVKPFDFVVF
130 140 150 160 170 180
INRIRELVSN RVTQVEPKPR PVQETQMTRS DFVKNVGNIE TEITNIIHEI GVPAHIKGYL
190 200 210 220 230 240
YLREAMKMVI DNVELLGAVT KELYPSIAKK FNTTPSRVER AIRHAIEVAW SRGKVDTINQ
250 260 270
LFGYTVHNTK GKPTNSEFIA MIADKLRLEH SMVK