P52833

PR
Gene name
thrS
Protein name
Threonine--tRNA ligase
Names
Threonyl-tRNA synthetase, ThrRS
Species
Pseudomonas syringae pv syringae
KEGG Pathway
EC number
6.1.1.3: Ligases forming aminoacyl-tRNA and related compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-61 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P52833

Entry ID Method Resolution Chain Position Source
AF-P52833-F1 Predicted AlphaFoldDB

No variants for P52833

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P52833

No associated diseases with P52833

7 regional properties for P52833

Type Name Position InterPro Accession
domain Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) 318 - 528 IPR002314
domain TGS 1 - 61 IPR004095
domain Anticodon-binding 541 - 630 IPR004154
domain Aminoacyl-tRNA synthetase, class II 243 - 534 IPR006195
domain Threonyl/alanyl tRNA synthetase, SAD 170 - 219 IPR012947
domain Threonine-tRNA ligase catalytic core domain 242 - 539 IPR033728
domain Threonine-tRNA ligase, class IIa, anticodon-binding domain 539 - 629 IPR047246

Functions

Description
EC Number 6.1.1.3 Ligases forming aminoacyl-tRNA and related compounds
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
threonine-tRNA ligase activity Catalysis of the reaction: ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr).
tRNA binding Binding to a transfer RNA.

1 GO annotations of biological process

Name Definition
threonyl-tRNA aminoacylation The process of coupling threonine to threonyl-tRNA, catalyzed by threonyl-tRNA synthetase. The threonyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a threonine-accetping tRNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
DIELKLSTRP EKRVGSDELW DRAESALASA LDSAGQPYDL QPGEGAFYGP KIEFSLKDCL
70 80 90 100 110 120
GRVWQCGTLQ LDFNLPIRLS AEYVSEDNSR KNPVMLHRAI LGSFERFIGI LIEHYEGAFP
130 140 150 160 170 180
AWLAPTQAVI MNITDKQADF ALEVEKTLAE SGFRAKSDLR NEKIGFKIRE HTLLKVPYLL
190 200 210 220
VIGDREVEMQ TVAVRTREGA DLGSMPVAQF AEFLAQAVSR RGRQDTE