P52698

PR
Gene name
phcA (RSc2748, RS00106)
Protein name
HTH-type transcriptional regulator PhcA
Names
Virulence genes transcriptional regulator PhcA
Species
Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
KEGG Pathway
rso:RSc2748
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

284-347 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P52698

Entry ID Method Resolution Chain Position Source
AF-P52698-F1 Predicted AlphaFoldDB

11 variants for P52698

Variant ID(s) Position Change Description Diseaes Association Provenance
92 L>A strain: AW1 and ACH0158 [UniProt] No
100 I>V strain: AW1 and ACH0158 [UniProt] No
185 H>G strain: ACH0158 [UniProt] No
185 H>R strain: AW1 [UniProt] No
206 T>S strain: AW1 and ACH0158 [UniProt] No
247 M>L strain: AW1 and ACH0158 [UniProt] No
262 T>A strain: AW1 and ACH0158 [UniProt] No
264 N>S strain: ACH0158 [UniProt] No
314 I>N strain: AW1 and ACH0158 [UniProt] No
329 S>A strain: AW1 and ACH0158 [UniProt] No
347 V>A strain: AW1 and ACH0158 [UniProt] No

No associated diseases with P52698

2 regional properties for P52698

Type Name Position InterPro Accession
domain Transcription regulator HTH, LysR 4 - 64 IPR000847
domain LysR, substrate-binding 94 - 304 IPR005119

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
protein-DNA complex A macromolecular complex containing both protein and DNA molecules.

2 GO annotations of molecular function

Name Definition
DNA-binding transcription activator activity A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets.
transcription cis-regulatory region binding Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVNVDTKLLV IFVELLSKRN ATYVAEKMHM TAPAVSHSLG RLREIFDDPL FIRVPHGLTP
70 80 90 100 110 120
TPKALELGPK VREMLDLWAA INEGDIATFD PLEAAGTFNI SFAGTLGDAL FDRFLLRVKR
130 140 150 160 170 180
LAPGLQVRLT ESSSWEADVA AMRSNELDLA FSPFPTRHPE IVEEVVTSFN MWVCARKDHP
190 200 210 220 230 240
VLKDHCSLDQ YLECEHIFIA QGNPGTRAAP SLIPLDYALQ QRGLKRHSTM TVHAWRTQAE
250 260 270 280 290 300
VAAQTDMIFT VNSLMKDLVC ETYNLNAFPL PSELETVLGL NMLWHRSRNT HPMLVWARNL
310 320 330 340
FKQVVAEYTG KASIAPMHPP MLTDDSGKSG KTGKGDAEKE DESRLSV