P52497

PR
Gene name
SNF1
Protein name
Carbon catabolite-derepressing protein kinase
Names
Species
Candida albicans (Yeast)
KEGG Pathway
EC number
2.7.11.1: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-80 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

192-214 (Activation loop from InterPro)

Target domain

53-305 (Protein kinase domain)

Relief mechanism

Assay

References

Autoinhibited structure

Activated structure

1 structures for P52497

Entry ID Method Resolution Chain Position Source
AF-P52497-F1 Predicted AlphaFoldDB

No variants for P52497

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P52497

No associated diseases with P52497

5 regional properties for P52497

Type Name Position InterPro Accession
domain Protein kinase domain 53 - 305 IPR000719
active_site Serine/threonine-protein kinase, active site 171 - 183 IPR008271
domain Carbon catabolite-derepressing protein kinase, ubiquitin-associated domain 328 - 385 IPR013896
binding_site Protein kinase, ATP binding site 59 - 82 IPR017441
domain AMPK, C-terminal adenylate sensor domain 487 - 613 IPR032270

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
  • Nucleus membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nuclear membrane Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

2 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSEQAQPQAS ADQQQHQHNH HHHHHHHHHN ENQSQQQVPI DPAANPANRI GRYQILKTLG
70 80 90 100 110 120
EGSFGKVKLA QHLGTGQKVA LKIINRKTLA KSDMQGRVER EISYLRLLRH PHIIKLYDVI
130 140 150 160 170 180
KSKDEIIMVI EFAGKELFDY IVQRGKMPED EARRFFQQII AAVEYCHRHK IVHRDLKPEN
190 200 210 220 230 240
LLLDDQLNVK IADFGLSNIM TDGNFLKTSC GSPNYMPAPE VISGKLYAGP EVDVWSAGVI
250 260 270 280 290 300
LYVMLCGRLP FDDEFIPALF KKISNGVYTL PNYLSAGAKH LLTRMLVVNP LNRITIHEIM
310 320 330 340 350 360
EDDWFKQDMP DYLLPPDLSK NKNSKIDVDE DVIRALSVTM GYDRDCKIVN VIEKANKQVA
370 380 390 400 410 420
AGNSSSQQSK SSNEILDAYL LMKENHALVK DLKKSKSENI ESFLSQSPPP SPFPNRGSTS
430 440 450 460 470 480
SAPGVQQSLT YQTLATVPDL STLPNSTIAI LPTSLPSIHR AYMAETKQNG DPSQQHAPPP
490 500 510 520 530 540
TKKSKTRWHF GIRSRSYPLD VMGEIYRALK NLGAEWAKPT EEELWTIRVR WKYDTSAQFE
550 560 570 580 590 600
CGSAPNLMKM QIQLFQLEPN NYLVSFKFSG WESAHGNAGT DSPQSHRQQD LDEVGSFSAY
610
PFLHLATRLI MELAVNSQSG