P52276

PR
Gene name
asnS
Protein name
Asparagine--tRNA ligase
Names
Asparaginyl-tRNA synthetase, AsnRS
Species
Synechocystis sp (strain PCC 6803 / Kazusa)
KEGG Pathway
syn:sll0495
EC number
6.1.1.22: Ligases forming aminoacyl-tRNA and related compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

41-118 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P52276

Entry ID Method Resolution Chain Position Source
AF-P52276-F1 Predicted AlphaFoldDB

No variants for P52276

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P52276

No associated diseases with P52276

3 regional properties for P52276

Type Name Position InterPro Accession
domain Aminoacyl-tRNA synthetase, class II (D/K/N) 117 - 456 IPR004364
domain OB-fold nucleic acid binding domain, AA-tRNA synthetase-type 19 - 98 IPR004365
domain Aminoacyl-tRNA synthetase, class II 144 - 452 IPR006195

Functions

Description
EC Number 6.1.1.22 Ligases forming aminoacyl-tRNA and related compounds
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
asparagine-tRNA ligase activity Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H(+).
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
nucleic acid binding Binding to a nucleic acid.

1 GO annotations of biological process

Name Definition
asparaginyl-tRNA aminoacylation The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an asparagine-accetping tRNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNKRRIIEVL RHGQADDQVM VQGWLRTKRT LKDFSFVEVN DGSSLANLQV VLDGSLADYD
70 80 90 100 110 120
RLLSQLQTGA ALVVEGKLAP SPGKGQRVEL KATKLELLGG ADPGSYPLQK KRHSFEFLRT
130 140 150 160 170 180
IGHLRPRTNT IGAVMRVRNA CATAIHQFFQ ERGFLWVHTP IITASDCEGA GDLFKVTTLD
190 200 210 220 230 240
LQRVPKNGEG IDYSQDFFGK QAYLTVSGQL EAEVMALAFQ NVYTFGPTFR AENSNTSRHL
250 260 270 280 290 300
AEFWMVEPEM AFCDLEGDRQ WAEEFLKYIF KFVLEKCPED MEFFDQRIDN TVLATADNII
310 320 330 340 350 360
NNEFAWLTYS EAIKLLEKAD QKFEYPVAWG VDLQSEHERY LAETVFKRPT IVTDYPKDIK
370 380 390 400 410 420
AFYMRLNDDG KTVAAMDILA PKIGEIIGGS QREERLDILT QRMQEQGVPE EDLWWYLDLR
430 440 450 460
RYGSVPHAGF GLGFERIVQF MTGMANIRDV IPFPRTPMNA EF