P52153
Gene name |
rho |
Protein name |
Transcription termination factor Rho |
Names |
ATP-dependent helicase Rho |
Species |
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422) |
KEGG Pathway |
dra:DR_1338 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P52153
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P52153-F1 | Predicted | AlphaFoldDB |
No variants for P52153
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P52153 | |||||
No associated diseases with P52153
6 regional properties for P52153
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain | 166 - 371 | IPR000194 |
| domain | AAA+ ATPase domain | 177 - 363 | IPR003593 |
| domain | Rho termination factor, N-terminal | 15 - 57 | IPR011112 |
| domain | Rho termination factor, RNA-binding domain | 58 - 133 | IPR011113 |
| domain | Cold shock domain | 62 - 126 | IPR011129 |
| domain | Transcription termination factor Rho, ATP binding domain | 164 - 412 | IPR041703 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP-dependent activity, acting on RNA | Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction. |
| helicase activity | Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix. |
| hydrolase activity | Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA-templated transcription termination | The completion of transcription: the RNA polymerase pauses, the RNA-DNA hybrid dissociates, followed by the release of the RNA polymerase from its DNA template. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTVTEVAPQA | LPFQELQEKI | LPELHLLAAG | LGIENYRKLK | KDALALAIME | KQADAEGQSL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ARGYLDITSD | GYGFLQADLL | DPASRSVLVT | AGVIKQYHLR | TGDEVIGRAR | KPRENERYGS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LVRVEAVNGL | DPEAARQRPR | FDDLTPTFPD | QQLVLEDPST | DDGLSLRVVD | LLVPIGRGQR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ALIVAPPKAG | KTTLLKKIAN | SITKNYPDVT | VMVLLVDERP | EEVTDFRESV | QGAQVIASTF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DEPPQHHVRV | AEFVHERARR | IVEEGGHVVI | LLDSITRLAR | ANNLVTPPTG | RTLSGGLDSN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ALHWPKRFLG | AARNIREGGS | LTILATALVE | TGSRMDDVIF | EEFKGTGNAE | LVLSRRLEER |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RIFPALDILK | SGTRREELLL | QPEVLKKMWL | LRKVISDMDP | ADAMEMLLGR | MGKTRNNVEF |
| LAALAG |